They reported anatomical success in 58% of patient and functional success in 42% of patients in their pilot study.3 In further studies, they improved upon their results as their understanding of pathogenesis behind macular hole improved.4 Afterwards, various modifications were introduced in IMH surgery and the most notable was Internal Limiting Membrane
Zhang, "Persistent unsealed internal limiting membrane
after Nd:YAG laser treatment for valsalva retinopathy," BMC Ophthalmology, vol.
Lois, "Full-Thickness Macular H, Internal Limiting Membrane
Peeling Study G: cost-effectiveness of internal limiting membrane
peeling versus no peeling for patients with an idiopathic full-thickness macular hole: results from a randomised controlled trial," British Journal of Ophthalmology, vol.
Ohno, "Staining of internal limiting membrane
in macular hole surgery," Archives of Ophthalmology, vol.
Ciardella, "Retinal nerve fiber layer thickness modification after internal limiting membrane
peeling," Retina, vol.
MH is sight-threatening and not uncommon; however, not until 1991 did Kelly and Wendel reported it to be treatable via internal limiting membrane
(ILM) peeling assisted pars plana vitrectomy (PPV), which was later established to be a standard surgical technique for this condition.[sup] The second milestone of MH surgery was laid by Kadonosono et al .
reported Nd:YAG laser photodisruption of hemorrhagic detachment of the internal limiting membrane
in 1989 and it has been used for Valsalva retinopathy since that report .
Currently, the classic procedure for treating IMH is pars plana vitrectomy with peeling of the internal limiting membrane
and intraocular gas tamponade, followed by a face-down position for several days [4, 5].
Value of internal limiting membrane
peeling in surgery for idiopathic macular hole stage 2 and 3: a randomised clinical trial.
Triamcinolone acetonide-assisted peeling of the retinal internal limiting membrane
for macular surgery.
The foveal thickness (FT) was measured as the distance between the internal limiting membrane
and inner border of the retinal pigment epithelium at the foveal centre with the computer-based caliper built into the OCT system.