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an inflammatory disease that originates in folds of the skin where there is friction between contiguous surfaces.
The causative factors of intertrigo include increased secretions of sebum and perspiration, enuresis, discharges from fistulas or hemorrhoids, and inadequate drying of skin folds after bathing. Intertrigo can arise between any contiguous surfaces, including the interdigital spaces of the feet (more rarely, of the hands), in the armpits, under the breasts, and in the folds of the abdomen and neck in obese persons. The first symptom is erythema; this is followed by the appearance of nonbleeding cracks in the depths of the folds. In neglected cases the cornified layer of the skin is torn away and erosive patches are formed. The course of intertrigo can be prolonged if infection sets in. The disease is treated by removing the causative factors and using anti-inflammatory agents. Intertrigo is prevented with hygienic skin care and elimination of the causes of increased perspiration and sebum secretion.