Running jostles the intestines, reduces blood flow to the intestines as the body sends more blood to the exercising muscles, stimulates changes in intestinal hormones
that hasten transit time, and alters absorption rate.
Contributing factors include "jostling" of the intestines, reduced blood flow to the intestines as the body diverts blood flow to the working muscles, changes in intestinal hormones
, altered absorption and dehydration.
These novel molecules simultaneously stimulate two receptors (GLP-1 and GIP) and consequently maximize metabolic effects compared to each of the individual molecules, or currently available medicines that are based on individual intestinal hormones