The PCNA positive cells stained yellow that were mainly scattered in the nucleus of intestinal crypt cells (intestinal glands) whereas only a few were present in lamina propria of intestinal villus
. The number of positive cells of PCNA increased significantly (p <0.01) in 80, 160, 320 and 640 mg/L group, compared with control group (Fig.
It has been reported that intestinal villus
length crypt depth mucosa thickness and villus surface area represent key parameters for intestinal digestion and absorption functions (Han 1991).
According to data analysis, the visfatin group showed a more significant decrease in the intestinal villus
area than the control group, and the LPS group was more significantly decreased than the visfatin+LPS co-stimulated group in terms of villus area (Figs.
Recovery responses of chick intestinal villus
morphology to different refeeding procedures.
Effect of diets different qualities of barley on growth performance and serum amylase and intestinal villus
Reports on the effects on feeding PKE diets on intestinal villus
height and crypt depth were inconsistent.
The intestinal villus
and crypt morphology has been associated with intestine function and growth in animals.
Some researchers have indicated that probiotic addition resulted in an increase of intestinal villus
height (Chichlowski et al., 2007; Awad et al., 2009).
As an energy source for the maturation of the mucosa cells of the chicken (Maiorka et al., 2000), Gln could improve the intestinal villus
height, intestinal relative weights, villus density, microvilli width, and surface area of the tip of the enterocytes in poults (Yi et al., 2001; Bartell et al., 2007; Fischer da Silva et al., 2007a; Murakami et al., 2007).
The intestinal crypt and epithelium mucosae of mammals was divided into the five regions, including the region of the stem cell and Paneth's cell in basilar part, the region of proliferation cell in the middle part of intestinal gland, the region of maturation in upper half of intestinal gland, function region and shedding part of upper half of intestinal villus
. However, the functional partition of chicken intestinal gland has not been reported yet.
CORT administration causes decreased small intestinal villus
height (Hu and Guo, 2008), which leads to a decline of absorptive area (Yamauchi and Tarachai, 2000), and the shortened small intestine length induced by CORT administration further lowered total absorption area of the small intestine, and subsequently decreased the small intestinal absorptive capacity.