intracellular enzyme


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intracellular enzyme

[¦in·trə′sel·yə·lər ′en‚zīm]
(biochemistry)
An enzyme that remains active only within the cell in which it is formed. Also known as organized ferment.
References in periodicals archive ?
Aminopeptidases are a family of intracellular enzymes involved in the supply of amino acids that are essential for cell growth.
Assays of the activities of these mainly intracellular enzymes form part of the indirect determination of the activity of free radicals.
These intracellular enzymes are involved in signaling pathways of many receptor-linked tyrosine kinases which are involved in growth, proliferation and differentiation of cancer cells.
Interferon Alpha-2b is thought to function by triggering an antiviral response within infected cells, by activating certain intracellular enzymes which cause degradation of viral RNA, and by mobilizing the body's natural immune system to destroy the infected cells.
The therapeutic window further can be improved if the cytotoxic agent is a prodrug only activated by intracellular enzymes.
The stability in plasma coupled with the highly efficient release of active drug by intracellular enzymes suggest that there may be a wide therapeutic window for ADCs prepared with these enzyme-cleavable linkers.
MAP kinases are intracellular enzymes that play a critical role in the regulation of cell growth.
Both proteins belong to different druggable classes of intracellular enzymes, but their involvement in stroke was previously unknown.

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