Three intracellular enzymes
viz, oxidase, catalase and urease were studied in all isolates and nitrate reduction tests was studied only for Bacillus species.
The mechanism of action of finasteride is to inhibit the steroid 5-alpha reductase, which is an intracellular enzyme
that converts testosterone into the potent androgen 5-alpha dihydrotestosterone (DHT).
PhaseRx is a biopharmaceutical company dedicated to developing mRNA products for the treatment of children with inherited enzyme deficiencies in the liver using intracellular enzyme
replacement therapy (i-ERT).
According to the company, PRX-OTC is an intracellular enzyme
replacement therapy (i-ERT) designed to replace the missing or defective enzyme inside the cells of patients with OTCD.
The intracellular enzyme
activity was observed under wide ranges of pH (5-9), temperature (30degC-90degC) and metal ions (Na+, Mg2+, Mn2+, Zn2+ and Cu2+).
Purification and characterization of an intracellular enzyme
with beta-glucosidase and beta-galactosidase activity from the thermophilic fungus Talaromyces thermophilus CBS 236.58.
D-Amino acid Oxidase is intracellular enzyme
. The acetone disrupts the cell membranes and the enzyme extudes out.
tTG, an intracellular enzyme
, has recently been proposed as the major autoantigen of anti-endomysial antibodies (EMAs), and measurements of IgA anti-tTG antibodies are used in the diagnostic evaluation of celiac disease (CD) (2-4).
The mechanism of action of these compounds is novel and involves, among many findings, the activation of a specific phosphatase, a specific intracellular enzyme
Regenacy's lead clinical candidate, ricolinostat (ACY-1215), and the non-clinical proof-of-concept compound, ACY-1083, each selectively inhibit the intracellular enzyme
HDAC6, a histone deacetylase that is known to have specificity for cytoplasmic, non-histone cellular proteins.
Acetylon said that selective inhibition of the intracellular enzyme
HDAC6 may offer enhanced anti-cancer effectiveness through potentially reduced side effects and improved tolerability compared to current non-selective inhibitors, which are active against both Class I and Class II HDACs.