intracellular signaling protein

intracellular signaling protein

[‚in·trə¦sel·yə·lər ′sig·nəl·iŋ ‚prō‚tēn]
(cell molecular)
One of a series of intracellular proteins that mediates a cell's response when an extracellular signal molecule binds to a receptor protein on the cell's surface, either by changing the cell's metabolism or shape, or movement, or gene expression.
References in periodicals archive ?
The articles report on the role an intracellular signaling protein, MyD88, plays in the development of liver and colon cancer in mice.
One specific intracellular signaling protein worth mentioning is the Ras protein group.
The nurse, physician and pharmacist are all important intracellular signaling proteins bringing Fred closer to the goal of feeling better.
Aptosyn(R) is a cGMP phosphodiesterases (cGMP-PDEs) inhibitor which leads to the activation of the intracellular signaling protein, Protein Kinase G (PKG), and subsequent stimulation of apoptosis through the c-Jun kinase pathway.
OSI-461 and Aptosyn(R) are cGMP phosphodiesterase (cGMP-PDEs) inhibitors which are designed to lead to sustained activation of the intracellular signaling protein, Protein Kinase G (PKG), and subsequent stimulation of apoptosis through the c-Jun kinase pathway.
Reddy's presentation will showcase the role of an intracellular signaling protein in uncontrolled smooth muscle proliferation, a process that triggers cardiovascular disorders including restenosis and atherosclerosis.
This presentation will highlight the role of this intracellular signaling protein in the expression of pro-inflammatory genes.
This is the first publication of a selective small-molecule drug that targets Src tyrosine kinase, an intracellular signaling protein that is critical to the osteoporosis disease process, and blocks Src-mediated cellular activities and bone breakdown.
The goal of the collaboration has been to develop novel, small-molecule drugs that block the activity of Src, an intracellular signaling protein that is critical to the osteoporosis disease process.
BioImage has pioneered the development of assays using our patented Green Fluorescent Protein to track the movement of intracellular signaling proteins in living cells and in real time," said Ole Thastrup, chief technical officer for BioImage.
The phosphorylation state of intracellular signaling proteins is an important indicator of biological function and is useful in the characterization of disease.
Specifically, the research collaboration will seek to identify novel small organic molecule compounds which act as antagonists, or inhibitors, of the molecular interaction between the CD40 receptor and one of its associated intracellular signaling proteins.
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