intracellular signaling protein

intracellular signaling protein

[‚in·trə¦sel·yə·lər ′sig·nəl·iŋ ‚prō‚tēn]
(cell molecular)
One of a series of intracellular proteins that mediates a cell's response when an extracellular signal molecule binds to a receptor protein on the cell's surface, either by changing the cell's metabolism or shape, or movement, or gene expression.
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The articles report on the role an intracellular signaling protein, MyD88, plays in the development of liver and colon cancer in mice.
Aptosyn(R) is a cGMP phosphodiesterases (cGMP-PDEs) inhibitor which leads to the activation of the intracellular signaling protein, Protein Kinase G (PKG), and subsequent stimulation of apoptosis through the c-Jun kinase pathway.
The collaboration has focused on developing novel, small-molecule drugs that block the activity of Src, an intracellular signaling protein that is critical to the osteoporosis disease process.
OSI-461 and Aptosyn(R) are cGMP phosphodiesterase (cGMP-PDEs) inhibitors which are designed to lead to sustained activation of the intracellular signaling protein, Protein Kinase G (PKG), and subsequent stimulation of apoptosis through the c-Jun kinase pathway.
The goal of the collaboration is to develop novel, small-molecule drugs that block the activity of Src, an intracellular signaling protein that is critical to the osteoporosis disease process.
Reddy's presentation will showcase the role of an intracellular signaling protein in uncontrolled smooth muscle proliferation, a process that triggers cardiovascular disorders including restenosis and atherosclerosis.
Nasdaq: ARIA) announced today that it has licensed the rights to the gene for FAS, an intracellular signaling protein that is critically involved in apoptosis, or programmed cell death.
This is the first publication of a selective small-molecule drug that targets Src tyrosine kinase, an intracellular signaling protein that is critical to the osteoporosis disease process, and blocks Src-mediated cellular activities and bone breakdown.
The goal of the collaboration has been to develop novel, small-molecule drugs that block the activity of Src, an intracellular signaling protein that is critical to the osteoporosis disease process.
The Company is targeting an intracellular signaling protein, called Src, which appears to play a critical role in activating osteoclasts, the cells responsible for bone degradation.
Specifically, Epitome will develop reagents for the quantitative measurement of key intracellular signaling proteins.
BioImage has pioneered the development of assays using our patented Green Fluorescent Protein to track the movement of intracellular signaling proteins in living cells and in real time," said Ole Thastrup, chief technical officer for BioImage.
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