In particular, for early gastric cancer (or high-grade intraepithelial neoplasia
), the sensitivities of microscopic diagnoses determined using the BLI approaches were over 90%, and the consistency between microscopic and pathological diagnoses was significantly superior for these approaches than for white light alone (p<0.05).
Differentiated-type vulval intraepithelial neoplasia
has a high-risk association with vulval squamous cell carcinoma.
Vaginal intraepithelial neoplasia
(VAIN) following hysterectomy in patients treated for carcinoma in situ of the cervix.
Mucin 1, 4 and 5AC expressions in correlation with clinicopathological parameters in pancreatic intraepithelial neoplasia
HPV 16 and cigarette smoking as risk factors for high-grade cervical intraepithelial neoplasia
. Int J Cancer 1998;78(3):281-5.
Cervical Intraepithelial Neoplasia
(CIN) - Products under Development by Companies 10
Feng, "Cervical intraepithelial neoplasia
," Journal of Practical Oncology, vol.
* The report reviews pipeline therapeutics for Cervical Intraepithelial Neoplasia
(CIN) by companies and universities/research institutes based on information derived from company and industry-specific sources
Then the researchers checked national databases to see which women developed cervical intraepithelial neoplasia
(CIN) or invasive cervical cancer.
It was concluded that colposcopy does help to identify the best site for biopsy and diagnosis of intraepithelial neoplasia
. It is noteworthy that colposcopy with directed biopsy detects intraepithelial neoplasia
grade III in two-third cases, with greater sensitivity when two or more biopsies are performed.26 A study analysed three clinical trials to find out the accuracy of colposcopic biopsy and concluded that more than one biopsy improved the colposcopic accuracy.
Most of these cases carry low risk of Cervical Intraepithelial Neoplasia
Stage III (a premalignant condition that is indicative of higher risk of cervical cancer), especially when not associated with HPV-positivity.
The second RCT, including both MSM and heterosexual men, found that qHPV vaccine reduced rates of persistent HPV infection by 48%, and external genital lesions (condylomata or intraepithelial neoplasia
involving the penis, perineum, or perianal area) by 66% associated with HPV types 6, 11, 16, and 18 using the intention-to-treat protocol.