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(hī'pərplā`zhə): see hypertrophyhypertrophy
, enlargement of a tissue or organ of the body resulting from an increase in the size of its cells. Such growth accompanies an increase in the functioning of the tissue. In normal physiology the growth in size of muscles (e.g.
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The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



an increase in the number of structural elements of tissues or organs. In man and animals, hyperplasia is based on the intensified reproduction of cells and the formation of new structures. Hyperplasia is observed in various types of pathological growth of tissues (chronic productive inflammation and tumor), in regeneration, and in hypertrophy. Hyperplasia often carries with it compensating characters. In plants, it may be a local growth of tissues resulting from mitotic or amitotic cell division. It occurs with infection by destructive or pathogenic organisms, during trauma, and under the influence of growth stimulants, pesticides, and other preparations. The result of hyperplasia is the formation of galls, calluses, and warts.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


Increase in cell number causing an increase in the size of a tissue or organ.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Intravascular papillary endothelial hyperplasia in a thrombosed renal allograft vein.
Intravascular papillary endothelial hyperplasia: Light and electron microscopic observations of a case.
Immunohistochemistry of intravascular papillary endothelial hyperplasia. J Cutan Pathol 1990;17:16-21.
Intravascular papillary endothelial hyperplasia: A neoplastic "actor" representing an exaggerated attempt at recanalization mediated by basic fibroblast growth factor.
Intravascular papillary endothelial hyperplasia. A benign lesion mimicking angiosarcoma.
Intravascular papillary endothelial hyperplasia. Multiple lesions simulating Kaposi's sarcoma.

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