Inulin

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inulin

[′in·yə·lən]
(biochemistry)
A polysaccharide made up of polymerized fructofuranose units.

Inulin

 

(C6H10O5), an organic substance of the polysaccharide group, a D-fructose polymer. It is a white powder, readily soluble in hot water and poorly soluble in cold. Sweet-tasting, it has a molecular weight of 5,000–6,000. Its structural formula is

During hydrolysis, inulin forms D-fructose and a small quantity of glucose in the presence of acids and the enzyme inulase. Inulin and the intermediate products of its fermentative decomposition, that is, inulides, do not have reducing properties. An inulin molecule comprises a chain of 30–36 fructose radicals in furanose form. Like starch, inulin serves as a reserve carbohydrate and occurs in many plants, primarily in the family Compositae as well as in the families Campanulaceae, Liliaceae, Lobeliaceae, and Violaceae. The inulin content reaches 10–12 percent in the tubers and roots of the dahlia, narcissus, hyacinth, tuberose, chicory, and Jerusalem artichoke. Related carbohydrates (pseudoinulin, inulenin, levulin, helianthin, sinistrin, irisin) are nearly always found with inulin in plants; these carbohydrates yield D-fructose upon hydrolysis as does inulin.

Inulin is extracted from chicory or from the Jerusalem artichoke. It is readily assimilated by the human body and is there fore used in medicine as a starch and sugar substitute in diabetes mellitus. Inulin also serves as the starting material for the commercial preparation of fructose.

References in periodicals archive ?
Inulin clearance, according to Tanner (2003), is the virtual volume of plasma which contains inulin eliminated by the kidneys in a certain period of time.
Mean (SD) inulin clearance tended to be higher with corticosteroids, 127 (25) ml, * [min.
Because inulin clearance is commonly normalized for an average BSA of 1.
88) to GFR measured by inulin clearance than did SCr (r = 0.
As expected, we found an inverse correlation of homocysteine with the GFR measured as inulin clearance [r = -0.
Serum cystatin C concentrations were 25% higher (range, 19-31%) in transplanted children vs non-transplanted children having the same GFR determined by inulin clearance (4).
The gold standard for the evaluation of the glomerular filtration rate (GFR) is inulin clearance (CIn), but its widespread use is prevented by several technical difficulties (1).
To validate these findings, we extended our previous study on the correlation between inulin clearance ([C.