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A growth pattern of epithelial tumors in which the proliferating epithelial cells grow outward from a surface, accompanied by vascularized cores of connective tissue, to form a branching structure.



a benign tumor of man and animals; its basic structural element is a connective-tissue papilla covered with epithelium and containing vessels. The growth of the papillae in various directions sometimes gives a papilloma the appearance of a cauliflower. The presence of numerous papillomas is called papillomatosis. Papillomas are most commonly found on the skin, although they sometimes occur on mucous membranes. In man, they may be congenital or may result from chronic inflammatory irritation. Some papillomas are viral in origin, for example, those of the sexual organs. The recommended therapy is surgical removal.

Papillomatosis in animals is caused by locally specific viruses. It affects cattle, horses, dogs, and rabbits and occasionally goats, sheep, and wild animals. The infection is caused by diseased animals; natural infection results from contact between diseased and healthy animals. The disease is long in duration. Isolated coral-like papillomas appear and then spread. Their surface is dry, horny, and cracked. When injured, papillomas bleed and become infected and ulcerous. Diagnosis is based on clinical and histological examination. Treatment generally consists of surgical removal.


References in periodicals archive ?
A study on the clinical profile and management of inverted papilloma.
Out of 9 cases of papilloma studied in this series, 6 were squamous papillomas and 3 were inverted papillomas.
Potentially distinctive features of sinonasal inverted papilloma on MR imaging.
Inverted papilloma of urinary bladder: is long-term cystoscopic surveillance needed?
5 cm in diameter, in the same area of the first resected lesion, was unusual since it was characterized by a mix of papillary cancer and another part resembling benign morphology, similar to inverted papilloma.
Inverted papilloma is a locally invasive benign tumour of this region.
Inverted papilloma is a rare benign neoplasm that usually originates in the lateral nasal wall.
WHO/ISUP (1998)--WHO (2004) Consensus Classification for Urothelial (Transitional Cell) Lesions Normal Normal Hyperplasia Flat hyperplasia Flat lesions with atypia Reactive (inflammatory) atypia Atypia of unknown significance Dysplasia (low-grade intraurothelial neoplasia) Carcinoma in situ (high-grade intraurothelial neoplasia) Papillary neoplasms Papilloma Inverted papilloma Papillary neoplasm of low malignant potential Papillary carcinoma, low grade Papillary carcinoma, high grade* Invasive neoplasms # Option exists to add comment as to the presence of marked anaplasia.
Inverted papilloma is the next common, while Rhinosporidiosis and Fibrous dysplasia are rarely seen.