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Related to investigational: Investigational New Drug
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



in criminal procedure, the elucidation of those circumstances of a criminal case necessary for arriving at the correct decision. Soviet law distinguishes between preliminary and judicial investigation.

Preliminary investigation, a basic form of inquiry, is an important stage in a criminal case. Begun after the initiation of the criminal case, it includes investigatory actions for the purpose of collecting and verifying evidence, presentation of the charges, the selection of a measure of restraint, actions to protect the legal interests of the accused, the victim, the plaintiff, and other participants in the trial, and actions to remove the causes and conditions contributing to the crime. The preliminary investigation comes to an end, within a period established by law, with the drawing up of a bill of indictment or a decree on termination of the case (see also).

Judicial investigation is a stage in the trial, during which a court of the first instance, in formal judicial session, makes a direct investigation of the evidence; that is, it verifies the evidence gathered in the preliminary investigation and inquiry and gathers and verifies additional evidence. Judicial investigation is autonomous; it is a multifaceted and objective analysis—with direct, open, and oral proceedings and equal procedural rights for all participants in the trial—of all the case’s circumstances significant for arriving at a just and legal decision.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


A process conducted for the purpose of accident prevention which includes the gathering and analysis of information, the drawing of conclusions, including the determination of causes and, when appropriate, the making of safety recommendations (ICAO).
An Illustrated Dictionary of Aviation Copyright © 2005 by The McGraw-Hill Companies, Inc. All rights reserved
References in periodicals archive ?
Drug developers and manufacturers are reluctant to provide access to investigational treatments.
Investigational medicines remain in development and are usually limited in supply.
In 1987, the FDA established a process for treatment use of investigational drugs but the regulations did not describe the criteria or requirements necessary to authorize individual patient treatment use (Treatment Use of an Investigational Drug, 1987).
While NIAID tests the VSV-ZEBOV vaccine candidate as a prime-boost strategy, WRAIR is evaluating the investigational vaccine as a single injection.
Historically, patients accessed promising investigational drugs once the agents had moved along in the development process, typically around the time of phase III trials.
Despite the prominence of a recent court ease (18) and proposed federal legislation (19) addressing these issues, the extent to which FDA regulations restrict access to investigational drugs and whether public policy supports these restrictions have not been thoroughly analyzed in the legal, health policy, bioethics, or medical literature.
The FDA states that it has taken this action to focus a manufacturer ' s effort on applying GMP that is appropriate and meaningful for the manufacture of the earliest stage investigational drug products intended for use in Phase 1 clinical trials while ensuring safety and quality.
The study evaluated the immune response and safety profile of the investigational combination DTaP-IPV (diphtheria, tetanus, acellular pertussis-inactivated poliovirus) vaccine in children ages 4 to 6 years-old as compared to separately administered DTaP (INFANRIX[R]) and IPV (IPOL[R]) vaccines, when co-administered with measles, mumps and rubella (MMR) vaccine (M-MRII[R]) at a separate site.
In February 2006, an investigational (not licensed) VZIG product, VariZIG[TM] (Cangene Corporation, Winnipeg, Canada) became available under an investigational new drug application (IND) submitted to the Food and Drug Administration (FDA).
Manufacturers and laboratories producing investigational new drugs in Phase 1 studies are exempt from having to fully validate their manufacturing process under new FDA guidelines.
Locteron and BLX-883 are investigational drug candidates and have not been approved by the U.S.

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