Keywords: tetracycline, factorial design, liquid chromatography, mass spectrometry, dual ionization source
Shimadzu's DUIS ionization source
includes both the ESI and APCI (atmospheric pressure chemical ionization) sources.
Other enhancements include Chemical Ionization Source
and Backflush capabilities as standard on all GC/Q-TOF systems.
An ICP-MS would destroy organic molecules due to the energetic nature of the ionization source
(an inductively coupled argon plasma) required for removing an electron from a metal so that it can be detected.
Atmospheric pressure chemical ionization (APCI) is not a "soft" (low-energy) ionization source
, and APCI results would closely resemble those obtained with the ESI source.
The active exhaust atmospheric pressure ionization source
with a robust orifice vacuum interface significantly enhances quantitative robustness for difficult samples;
The Xevo also features the latest generation of Waters' ZSpray ionization source
, which is an integrated design that allows users to switch between various sources without any tools.
Samples were infused into the ionization source
using a syringe pump at 20 [micro]L/minute with the capillary temperature set at 200[degrees]C.
The Agilent 1100 Series LC/MSD Trap XCT Ultra ion trap mass spectrometer (G4533AA) includes mass spectrometer, electrospray ionization source
, data system and LC/MSD Trap software (6.
The new device includes improved dielectric barrier discharge ionization source
and high-voltage square wave generator which has been given superior voltage shielding.
Ionization inhibition in the ionization source
is another phenomenon that results in analyte loss or variations among samples.
In addition, the platform features several innovations such as a Vacuum-Insulated Probe, an active exhaust atmospheric pressure ionization source
and a tune-free Interlaced Quadrupole Dual Funnel.