iron metabolism


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iron metabolism

[′ī·ərn mə′tab·ə‚liz·əm]
(biochemistry)
The chemical and physiological processes involved in absorption of iron from the intestine and in its role in erythrocytes.
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References in periodicals archive ?
However, further studies are required to address the safety of this combination treatment and interspecies differences in iron metabolism between rats and human in addition to have better understanding of the role of the hepcidin.
Curcumin attenuates erythropoiesis in recombinant human erythropoietin-induced polycythemia in rats
Study Selection: Articles related to iron metabolism, iron overload in patients with CHC, or the effects of iron on HCV life cycle were selected for the review.
Relationship between Hepatitis C Virus Infection and Iron Overload
Measurement of sTfR is considered better for reflecting iron metabolism as its levels focus on both body iron stores and total erythropoiesis.
Stages of chronic kidney disease and soluble Transferrin Receptor (sTfR), Ferritin, ratio
Hepcidin, ferroportin-1 and transferrin are associated with iron metabolism and their expression can be affected under different physiological or pathological conditions.
HEPATIC IRON REGULATORY GENE EXPRESSION INFLUENCED DUE TO DISTURBED ESSENTIAL TRACE ELEMENTS LEVEL
The researchers also showed pathways caused by high doses of vitamin C by which altered iron metabolism in cancer cells lead to increased to sensitivity to cancer cell killing.
Large doses of vitamin C can boost cancer treatment: In a clincal trial, standard cancer therapies, such as radiation and chemotherapy, are enhanced via vitamin C infusions
In recent years, after the discovery of hepcidin, a negative regulator of iron metabolism, studies on thalassemia patients have suggested that the cause of increase in intestinal iron absorption may be the decrease in synthesis of hepcidin.
Serum Prohepcidin Levels in Children with Thalassemia Major and Intermedia / Talasemi Major ve Intermediali Cocuklarda Serum Prohepsidin Duzeyleri
The broad, yet vague, diagnostic term "anemia of chronic disease" best categorizes the complexity of events that lead to paradoxical disorders related to iron metabolism.
Iron anemia with paradoxical elevations of iron storage and metabolic iron utilization challenges
Moreover, the deficiency of other nutrients may coexist, such as vitamin A, which interact with iron metabolism and function.
Improvement the nutritional status of pre-school children following intervention with a supplement containing iron, zinc, copper, vitamin A, vitamin C and prebiotic/Melhoria no estado nutricional de pre-escolares apos intervencao com suplemento contendo ferro, zinco, cobre, vitamina A, vitamina C e prebiotico
The effects of E2 on intracellular iron metabolism in SKOV-3 were most evident at 5 nM/24 h dose.
Estrogen-Dependent downregulation of hepcidin synthesis induces intracellular iron efflux in cancer cells in vitro
Anaemia due to hypothyroidism is characterized by a small decrease of the half-life of red cells, caused either by a disturbance of the iron metabolism or by resistance to erythropoietin action.
Anaemia in hypothyroidism: a single centre study
It is unclear whether the hyperferritinemia is secondary to an acute-phase response or whether abnormal iron metabolism or a variant ferritin is involved in the pathogenesis of AOSD.
Commentary
Cellular iron metabolism and its epigenetic regulation are well-balanced and tightly controlled in normal cells [5].
Modulation of iron metabolism by iron chelation regulates intracellular calcium and increases sensitivity to doxorubicin

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