The basic system of iron metabolism involves the dietary iron absorption by the duodenal enterocytes (Ganz et al., 2012) via duodenal metal transporter-1 (DMT-1) (Gunshin et al., 2001), followed by delivery of iron to the tissues by means of transferrin (Dunn et al., 2007); an iron-binding protein
in plasma; fundamentally involved in iron transportation (Hentze et al., 2004; Morgan1981; Richardson et al., 1997).
Friedreich's ataxia (FRDA), an inherited, progressive neurodegenerative disease, is caused by a reduced expression of the mitochondrial iron-binding protein
The disease results from loss of function mutations (most often triplet expansion) in the FXN gene that lead to decreased expression of frataxin, a mitochondrial iron-binding protein
that interacts with proteins involved in the mitochondrial Fe-S cluster biogenesis .
Myoglobin, an iron-binding protein
, is the main pigment of red muscles, and its concentration in muscle is the most important factor responsible for meat color.
Washington, May 1 ( ANI ): Researchers have shed light on the several health benefits associated with lactoferrin, an important iron-binding protein
The foregoing antioxidant scheme has been adequately explained for the iron-binding protein
The molecule, an iron-binding protein
called lactoferrin, could form the basis of a new treatment for osteoporosis, says study leader Jillian Cornish of the University of Auckland in New Zealand.
A previously little-understood iron-binding protein
, ovotransferrin (OTF), is abundant in poultry blood and eggs.
Lactoferrin, an iron-binding protein
found in milk, is a powerful MBA.
Most important is it contains anti-bodies and iron-binding protein
that protects a baby.
Lactoferrin is a high-affinity iron-binding protein
found in blood and certain white cells, and is thought to protect against certain microbiological infections, destabilizing the outer membrane of gram-negative bacteria, and binding directly with toxic liposaccharides, preventing toxic shock and sepsis.