There is hyperalgesia and allodynia due to inflammatory process involved in irreversible pulpitis
, which hampers profound local anaesthesia.
The following variables were also evaluated: a) patient age at the time of therapy; b) region of treated teeth (anterior or posterior); c) arch of treated teeth (maxillary or mandibular); d) initial pulp condition (irreversible pulpitis
, necrosis without periapical or interradicular radiolucency, necrosis with periapical or interradicular radiolucency); e) cause of pulp pathology (caries or trauma); f) pre-operative clinical signs and symptoms (present or absent); g) pre-operative periapical or interradicular radiolucency (present or absent); h) level of root canal filling; and (i) integrity of crown restoration at follow-up visits.
The medicament was administered intraosseously in the are of posterior teeth of the mandibula to patients who were diagnosed with irreversible pulpitis
. According to the authors, the effectiveness of anaesthesia was obtained in 86% of patients .
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis
: a prospective, double-blind, randomized clinical trial.
It found no statistically significant difference (p=0.006).1 The previous studies conducted on the comparison of NaOCl and CHX included teeth with irreversible pulpitis
and necrotic teeth.
Sealed envelope method technique is used for randomizing the symptomatic irreversible pulpitis
A comparison of the efficacy of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine in achieving pulpal anesthesia in maxillary teeth with irreversible pulpitis
. J Endodod.
Dental pain associated with chronic irreversible pulpitis
(29.83%) and/or periapical abscess was the most common reason responsible for patient's visit to dental OPD for dental care.
 reported that putative stem cells isolated from teeth with irreversible pulpitis
showed decreased ability for colony formation and a slightly decreased cell proliferation rate but had similar levels of STRO-1 expression and exhibited a similar percentage of positive ex vivo osteogenic induction .
Methodology: Ninty emergency patients who had 1st molar diagnosed with irreversible pulpitis
participated in the study.
In contrast with these studies, however, Lindemann et al evaluated the effect of triazolam on the success rate of IANB in the patients with irreversible pulpitis
and reported that the success rate of IANB in triazolam (a kind of benzodiazepine) group showed no statistically significant difference in comparison with the placebo group .
Human dental pulpitis tissues were collected from teeth having a clinical diagnosis of irreversible pulpitis
(n = 15).