Ischemia

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ischemia

[i′skē·mē·ə]
(medicine)
Localized tissue anemia as a result of obstruction of the blood supply or to vasoconstriction.

Ischemia

 

a local deficiency of blood; insufficient blood in an organ or tissue because of the narrowing or complete occlusion of the lumen of an afferent artery.

Transitory ischemia (like hyperemia) may result from physiological regulation of the blood supply, such as in reflex spasm of an artery caused by a mental factor (fright); the influence of pain, cold, chemical substances (epinephrine, ergotin), and biological stimuli (bacteria, toxins); the obstruction of an artery by a thrombus or embolus; constriction of the lumen of a blood vessel in connection with an atherosclerotic or inflammatory process in the wall; or compression of an artery by a tumor, scar, or foreign body. The aftereffects of ischemia depend on the degree of disruption of the blood flow, the rate of development and duration of the ischemia, the sensitivity of the tissue to oxygen deficiency, and the general condition of the body. Ischemia may end in complete restoration of the structure and function of the affected organ or tissue, but it also may lead to necrosis (infarct). The central nervous system and heart muscle are particularly sensitive to ischemia.

N. R. PALEEV

References in periodicals archive ?
A previous case reported of a 39-year-old multiparous woman with PPCM who developed lower limb ischaemia, had atrial fibrillation as a predisposing factor.
Percutaneous cannulation of the femoral artery and/or vein provides a faster onset of supportive treatment, but ischaemia and compartment syndrome may be seen particularly in the distal lower extremity after femoral artery cannulation.
Transient ischaemic attack (TIA) is traditionally defined clinically by the temporary nature of the associated neurological symptoms, which last <24 hours owing to neurological dysfunction caused by focal brain, spinal cord or retinal ischaemia, without acute infarction.
The diagnosis of Myocardial Ischaemia depends upon the clinical evaluation of the patient and the ECG changes.
ACS is a cardiovascular disease characterized for ischaemia periods and triggered by inflammatory response [15].
This phenomenon may be observed in many different clinical conditions, such as intestinal ischaemia and/or necrosis, chronic obstructive pulmonary disease and steroid use.
Ischaemic preconditioning (IP) of skin flap describes a phenomenon where tolerance to ischaemia is induced through provision of a short-term, ischaemia-reperfusion cycle before the actual, longer period of ischaemia, as a result of surgical procedure.
Four cases had clinical symptoms of ischaemia with 2 mortalities: one due to ischaemic gut and the other related to surgical complications associated with resection of the ischaemic segment.
Taking all this information into consideration, there is no doubt that, compared to individuals without diabetes, those with diabetes have a higher prevalence of CHD, a greater extent of coronary ischaemia, and are more likely to suffer a myocardial infarction and silent myocardial ischaemia.
The clinical presentations of CAD include stable angina pectoris, silent ischaemia, unstable angina, MI, heart failure and sudden death.
Cardiac arrest; superior mesenteric artery occlusion; intestinal ischaemia.
When tissue is exposed to ischaemia, cellular function in the basal metabolism is impaired and a series of chemical events occur progressing as far as necrosis.