isocyanic acid


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Related to isocyanic acid: melamine, HCN

isocyanic acid

[¦ī·sō·sī′an·ik ′as·əd]
(organic chemistry)
HN‒C‒O One of two forms of cyanic acid; a gas used as an intermediate in the preparation of polyurethane and other resins.
References in periodicals archive ?
Urea decomposition, however, is not the sole pathway leading to isocyanic acid formation, especially in nonuremic patients.
Two mechanisms had been suggested to explain its beneficial action: direct interference of the urea molecule per se with sickling (18), and hemoglobin S carbamylation by urea-derived isocyanic acid, which increases oxygen affinity and decreases aggregation properties (19).
Because of the pathways of isocyanic acid formation in vivo, carbamylation is preferentially involved in 2 pathophysiological processes: CRF and atherosclerosis (26, 39, 40).
Isocyanic acid in the atmosphere and its possible link: o smoke-related health effects Proc Natl Acad So USA 108(22):8966-8971 (2011); hup://dx.
Although unstable, isocyanic acid, the reactive compound that binds to lysine residues during the carbamylation reaction, may be quantified after convenient derivatization and separation.