[USPRwire, Thu May 30 2019]
Isogenic cell lines are selectively reengineered human cells that are used as genetic models for a specific patient population.
This finding substantiated an
isogenic relationship between P-1 and P-3 and demonstrated that the [TR.sub.120] resistance mechanism emerged from P-1, probably during long-term azole therapy.
The
isogenic healthy control line did not display the same phenotype, confirming that the abnormalities were caused by the mutation.
eridania on 21.6 [+ or -] 0.7 a 56.4 [+ or -] 6.8 b non-Bt
isogenic (DOW 2B688) S.
For the analysis of all mitochondrial variables, except oxygen consumption, in osteosarcoma 143B cybrids, we used
isogenic cybrids (Owti and Om).
All these cells were
isogenic, which means they all had the same gene set.
For this study, we selected four types of sorghum, two
isogenic lines of grain sorghum (CMS-XS 114 with tannin and CMS-XS 165 without tannin) and two sorghum hybrids (BR-700 dual purpose with tannin and BR-601 forage without tannin).
Most R genes to BLB have been introgressed into the background of the susceptible indica cultivar to develop a set of near
isogenic lines (NILs), and some have been pyramided, either through classical breeding and marker-assisted selection or through genetic engineering, to develop new plant types and NILs (Sanchez et al., 2000; Singh et al., 2001; Narayanan et al., 2002).
The range of
isogenic iPSC (induced pluripotent stem cells)-derived neural cells include APOE knockout neurons and astrocytes, MAP2 and GFAP reporter lines, and a panel for assessment of neurotoxicity and neural protective drug candidates.
Under the terms of the agreement, Thermo Fisher will market and distribute Horizon's X-Man human haploid and diploid
isogenic cell line collection and will further offer Horizon's X-Man haploid cell line generation service to its worldwide customer base with the exception of Japan.