isogenic


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isogenic

[‚ī·sə·jə′nē·ik]
(genetics)
Having the same genotype, as all organisms of an inbred strain.
(immunology)
Referring to cells, tissues, or organs used in transplantation that originate in identical species.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
[USPRwire, Thu May 30 2019] Isogenic cell lines are selectively reengineered human cells that are used as genetic models for a specific patient population.
This finding substantiated an isogenic relationship between P-1 and P-3 and demonstrated that the [TR.sub.120] resistance mechanism emerged from P-1, probably during long-term azole therapy.
The isogenic healthy control line did not display the same phenotype, confirming that the abnormalities were caused by the mutation.
For the analysis of all mitochondrial variables, except oxygen consumption, in osteosarcoma 143B cybrids, we used isogenic cybrids (Owti and Om).
All these cells were isogenic, which means they all had the same gene set.
For this study, we selected four types of sorghum, two isogenic lines of grain sorghum (CMS-XS 114 with tannin and CMS-XS 165 without tannin) and two sorghum hybrids (BR-700 dual purpose with tannin and BR-601 forage without tannin).
Most R genes to BLB have been introgressed into the background of the susceptible indica cultivar to develop a set of near isogenic lines (NILs), and some have been pyramided, either through classical breeding and marker-assisted selection or through genetic engineering, to develop new plant types and NILs (Sanchez et al., 2000; Singh et al., 2001; Narayanan et al., 2002).
The range of isogenic iPSC (induced pluripotent stem cells)-derived neural cells include APOE knockout neurons and astrocytes, MAP2 and GFAP reporter lines, and a panel for assessment of neurotoxicity and neural protective drug candidates.
Under the terms of the agreement, Thermo Fisher will market and distribute Horizon's X-Man human haploid and diploid isogenic cell line collection and will further offer Horizon's X-Man haploid cell line generation service to its worldwide customer base with the exception of Japan.