Hemolytic disease of the newborn due to
isoimmunization with anti-E antibodies: a case report.
The anemia from anti-Kell
isoimmunization seems to be a combination of destruction of early red blood cells and suppression of red blood cell production.
This code also would be reported for the patient being tested for
isoimmunization with no test result at the time of the visit.
Management of pregnancies complicated by anti-Kell
isoimmunization. Obstet Gynecol.
The groups of the cause of death were defined according to [14] as congenital malformation,
isoimmunization, antepartum asphyxia, intrapartum asphyxia, birth trauma, pulmonary immaturity, hyaline membrane disease, intracerebral hemorrhage, infection, miscellaneous, unclassified, or unknown.
The combination of anemia, reticulocytopenia, hydrops fetalis, and a positive indirect Coombs test suggested Kell
isoimmunization. The baby was successfully treated with exchange transfusion of Kellnegative packed red cells, and was discharged on postnatal 30.
Intravascular fetal blood transfusion by cordocentesis represents a significant therapeutic advance for red blood cell
isoimmunization, or hemolytic disease of the newborn.
Rhesus
isoimmunization (RI) is a frequent cause of fetal anemia caused by the transport of maternal antibodies from the placenta and subsequently destroys fetal red blood cells.
In such cases of paternal heterozygosity, only 50% of the fetuses will be potentially at risk for
isoimmunization. Therefore, by establishing the paternal zygosity, improved counseling of couples concerning risks and treatment options can be provided.