isoprostanes

isoprostanes

[‚ī·sō′prä‚stānz]
(biochemistry)
A class of natural products that are isomeric with prostaglandins but are formed in vivo by the nonenzymatic, free-radical oxygenation of arachidonic acid.
References in periodicals archive ?
Non-enzymatic lipid peroxidation markers are isoprostanes (IsoP) produced in a phospholipid membrane under the influence of ROS [28].
Puede retrasar la aparicion de isoprostanes en la orina y plasma LDL en el tejido aortico.
Berliner, "Oxidized phospholipids and isoprostanes in atherosclerosis," Current Opinion in Lipidology, vol.
Carrier, "Plasma F2 isoprostanes: direct evidence of increased free radical damage during acute hyperglycemia in type 2 diabetes," Diabetes Care, vol.
Zhang et al., "Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases," Chemistry and Physics of Lipids, vol.
2005), to our knowledge, the relationship between As exposure and isoprostanes has not been evaluated in human populations.
In the first stage of oxidation, minimal modifications of LDL particles occur in the form of minimum modified apolipoprotein B, conversion of cholesteryl esters and phospholipids in hydroperoxides, isoprostanes and short length branched-chain aldehydes.
Block, in a study, demonstrated that the amount of lipid peroxidation and [F.sub.2] isoprostanes were increased significantly in smokers compared with nonsmokers (Block et al.,).
Furthermore, it may be utilized by the P450 metabolism to produce 20-HETE [53] and by nonenzymatic conversion to form [PGF.sub.2] isoprostanes [3, 54] (Figure 3(b)).
Veglia et al., "Isoprostanes and oxidative stress in off-pump and on-pump coronary bypass surgery," Annals of Thoracic Surgery, vol.