isosterism


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isosterism

[ī′säs·tə‚riz·əm]
(physical chemistry)
A similarity in the physical properties of ions, compounds, or elements, as a result of electron arrangements that are identical or similar.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Key words: Isosterism; Bioisosterism; SAR; Drug Design; 3D Chemical Structures.
Isosterism or bioisosterism is one of the approaches most frequently used in the design of new molecules [1].
Input of Isosteric and Bioisosteric Approach in Drug Design
Analogous compounds may be obtained through homologation, chain branching of aliphatic side chains, altering ring substitutions and substituents, ring-chain transformations, and isosterism. Silverman, supra note 10, at 26-29.
Deuterated drugs: unexpectedly nonobvious?
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