isothiocyanate


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isothiocyanate

[‚ī·sə‚thī·ō′sī·ə‚nāt]
(organic chemistry)
A compound of the type R‒N=C=S, where R may be an alkyl or aryl group; an example is mustard oil. Also known as sulfocarbimide.
References in periodicals archive ?
p53-Independent apoptosis by benzyl isothiocyanate in human breast cancer cells is mediated by suppression ofXIAP expression.
However, upon exposure to the environment, the chemical degrades to methyl isothiocyanate, a low melting and powerful lachrymator (5).
Concentrations of the bioactive condensed tannins (proanthocyanidins), L-dopa, and benzyl isothiocyanate in the lespedeza hay, mucuna seeds, and papaya seeds were within normal ranges of 8.7% to 18.1% [27], 2.2% to 5.4% [28], and 2 to 687 mg/kg [29], respectively.
The main inhibitory activity exhibited by the studied EO can be attributed to its main identified compound, allyl isothiocyanate, preventing the development of A.
Park, "Effects of microencapsulated Allyl isothiocyanate (AITC) on the extension of the shelf-life of Kimchi," International Journal of Food Microbiology, vol.
Hexakisphosphazenes bearing thioureas moieties have been reported from the stepwise reaction of the isolated isothiocyanate intermediates with a series of aliphatic amines via P-Cl substitution of hexachlorocyclotriphosphazene [13].
A number of electrophilic NRF2 activators, including naturally occurring isothiocyanates and semisynthetic triterpenoids, are currently in clinical trials, and an oral preparation of dimethyl fumarate (DMF, Tecfidera) is used in clinical practice to reduce disease progression in patients with relapsing remitting multiple sclerosis.
Putsep, "Benzyl isothiocyanate, a major component from the roots of Salvadora persica is highly active against Gram-Negative bacteria," PLoS ONE, vol.
Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L.
Apoptosis was determined by using the annexin V-fluorescein isothiocyanate (FITC) Apoptosis Detection kit (eBioscience, Frankfurt, Germany) according to the manufacturer's instructions.
Su-Hyeong Kim, Ph.D., will discuss how benzyl isothiocyanate, a molecule found in edible cruciferous vegetables, such as garden cress, works in breast cancer cells to decrease levels of Bmi-1, a protein that controls genes responsible for cell proliferation.