isotope dilution


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isotope dilution

[′ī·sə‚tōp də‚lü·shən]
(nucleonics)
The introduction of a radioisotope into stable isotopes of an element in order to make volume, mass, and age measurements of the element.
References in periodicals archive ?
Absolute quantification of phosphorylation on the kinase activation loop of cellular focal adhesion kinase by stable isotope dilution liquid chromatography/mass spectrometry.
The measurement of free thyroxine by isotope dilution tandem mass spectrometry.
Reduction of systematic errors in quantitative analysis by isotope dilution mass spectrometry (IDMS): an iterative method.
Reduced imprecision of quantification in targeted methods can be achieved by using isotope dilution, in which chromatographic peak areas of endogenous peptide-specific transitions are normalized to peak areas from stable-isotope-labeled internal standard peptide-specific transitions.
41) evaluated the effect of immunodepletion and prefractionation of plasma on reproducibility, LOD, and LOQ of MRM assays using stable isotope dilution MS for 6 proteins.
Quantification of cardiovascular biomarkers in patient plasma by targeted mass spectrometry and stable isotope dilution.
This analytical technique measures a surrogate peptide of the target protein (assuming molar equivalence between the protein and peptide) via stable isotope dilution internal standardization.
Determination of serum cholesterol by a modification of the isotope dilution mass spectrometric definitive method.
A comparison of calculation procedures for isotope dilution determinations using gas chromatography mass spectrometry.
Determination of folate vitamers in human serum by stable isotope dilution tandem mass spectrophotometry and comparison with radioassay and microbiologic assay.
Combined with isotope dilution using stable isotope-labeled peptides as internal standards ([IS.