isotypes

isotypes

[′ī·sə‚tīps]
(immunology)
A series of antigens, for example, blood types, common to all members of a species but differentiating classes and subclasses within the species.
Different classes of immunoglobulins that have the same antigenic specificity.
References in periodicals archive ?
The multiple RF isotypes should be tested as the predictive value for RA increases when more than one isotype is positive, Inova Diagnostics explained.
The subject of a public contract is the supply of original reagents and original operational consumables for the material assurance of the determination of total and specific ige (native and component antigens), specific igg / igg4 and possibly other ig and ecp isotypes (see tender specifications) and free rental and installation of appropriate analytical system for processing of diagnostics (see the tender dossier).
Netto and Vladutiu used immunoselection for the light-chain identification in such a case and noted this problem occurs more often with IgA and IgD M-proteins than with other isotypes (2).
In spite of the prevalence of anti-dsDNA IgM and IgA isotypes in SLE, they are not routinely measured during the follow-up of these patients, and their diagnostic values in SLE are still a topic of considerable interest.
When ASC from peptide-immunized NP animals were studied, IgM and IgG1 were the dominant isotypes of antibody detected in ML; high amounts of IgA ASC (>200 ASC/ 106 cells) were detected in animal 168.
The purpose of the present work was to evaluate salivary anti-phenolic glycolipid 1 antigen (PGL-1) IgA and IgM isotypes among 169 leprosy contacts aged 4-16 years living in the municipalities of Santana do Ipanema and Rio Largo (Alagoas state, Brazil).
A5 Amasya: Tasova, Borabay village to Basyurt Yayla, 9 km, 1382 m, serpentine slopes, roadsides, 16.08.2013, 40[degrees]48'011"N 36[degrees]07'005"E, A.Duran 9733 & O.Karabacak (holotype: KNYA; isotypes: GAZI, ANK).
Anticardiolipin antibody of IgG isotype and anti-b2 glycoprotein I antibodies of IgG and IgM isotypes were positive.
Recently we have demonstrated that anti-TF Abs in the serum (a pool of all Ig isotypes) of patients with gastric cancer show a significantly higher reactivity to sialic acid-specific Sambucus nigra lectin (SNA) than in controls [19].
In preclinical studies, VTP-43742 has been observed to inhibit RORI[sup.3]t activity, is highly selective versus other ROR isotypes and may provide a treatment that could be administered as a once-daily oral dose.
In preclinical studies, VTP-43742 has been observed to inhibit ROR[gamma]t activity, is highly selective versus other ROR isotypes and may provide a treatment that could be administered as a once-daily oral dose.