(redirected from Ivermectin)
Also found in: Dictionary, Thesaurus, Medical, Wikipedia.


Infection with the filaria Onchocerca volvulus ; results in skin tumors, papular dermatitis, and ocular complications.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a chronic parasitic disease that is caused by nematodes of the genus Onchocerca. Onchocerciasis occurs universally and mainly affects ungulates; the greatest economic damage arises when cattle and horses are affected. The intermediate hosts of Onchocerca are simuliids and ceratopogonids, which are bloodsucking insects. The infestation is most prevalent in pastures during the swarming time of the intermediate hosts. The mature parasites concentrate in the tendons, ligaments, and connective tissue, causing inflammatory foci that are often aggravated by pyogenic microflora.

Onchocerciasis usually occurs without observable symptoms. Diagnosis in the living animal is based on the presence of Onchocerca larvae in skin biopsies and on the results of allergic skin tests. No specific treatment is available. Onchocerciasis is prevented by protecting animals from the bites of simuliids and ceratopogonids and by exterminating these insects during hatching time, from May to August.


Skriabin, K. I., and A. M. Petrov. Osnovy veterinarnoi nematodologii. Moscow, 1964.
The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
With permethrin DOT, the impetigo rate dropped by 54%; with ivermectin DOT, the impetigo rate dropped by 67%.
Ivermectin (IVM) can have lethal and sublethal effects on both species, mainly affecting their reproductive capacity by diminishing egg production and larval development (Perez-Cogollo et al., 2015, 2017).
Any dog that consumes a large amount of horse faeces containing the chemical could become very ill, but a percentage of dogs of certain breeds have a gene mutation which makes them more susceptible to toxicity from ivermectin at low levels.
Present communication reports successful management of severe anaemia due to Haemonchus in sheep flock with Ivermectin and Iron supplementation.
Although the results were promising, trials need to take place in areas where malaria is common, and ivermectin needs to be tested on children for safety.
'Ivermectin has the potential to play a role in malaria elimination efforts and will address the current challenges of targeting mosquitoes that are resistant to the standard insecticides used on long lasting insecticidal nets and indoor residual spraying as well us mosquitoes that bite and rest outdoors,' he said.
Systemic signs include peripheral eosinophilia (Loeffler syndrome), migratory pulmonary infiltrates and increased immunoglobulin E (IgE) levels, but these are rarely seen.4,5 The disease is self- limiting resolving in weeks or months depending on the species of larva.1 Therapeutic options for CLM include a single dose of ivermectin (200 ug/kg body weight), oral albendazole 400mg daily for 5-7 days, thiabendazole (50mg/Kg body weight) for 2-4 days.
The falcons were dewormed yearly with a single subcutaneous injection of ivermectin (2 mg/ kg), except for two 1-year-old falcons (falcons 7 and 12) that had never been dewormed at the time of death of falcon 1.
Oxfendazole, Levamisole and Ivermectin, available in the market were determined by Faecal Egg Count Reduction Test (FECRT).
The Division of Global Migration and Quarantine of the Center for Disease Control and Prevention (since 2005) recommends prearrival ivermectin at a dose of 200 [micro]g/kg/day orally once a day for 2 days for those without contraindications [10].
Ivermectin is an analogue of avermectin, which belongs to a family of 16-membered macrocyclic lactones.