juglone


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juglone

[′jəg‚lōn]
(organic chemistry)
C10H6O3 A naphthoquinone derivative that occurs naturally in black walnuts and is toxic to plants.
References in periodicals archive ?
The interest in juglone has increased because of several further studies that revealed that juglone has cytotoxic and genotoxic effects against cultured melanoma tumor cell [12].
A volume of 10 [micro]L of 10 mM juglone (stock solution freshly prepared) was added to the micro tubes containing 1000 worms in 990 [micro]L of M9.
These findings may be explained by previous studies, showing that juglone (5-hydroxy-1,4-naphthoquinone) partially blocks voltage-dependent potassium channels, causing depolarization of the membrane [52].
Underlying the walnut's compelling disease-inhibiting benefits is an abundance of polyphenols, as well as the rare, anticancer phytonutrients juglone, tellimagrandin, and morin.
Some specific topics treated include green technology, "smart city" construction, architectural parametric design, an aquatic logistics model based on supply chain management, improvement of a headphone speaker production line, the effects of juglone on the migration of human ovarian cancer cells, and the design and implementation of an oilfield heterogeneous data-integration model based on ontology.
EPs7630[R] treatment reduces intracellular hsp-16.2::GFP expression (induced by the pro-oxidant juglone) indicating that the secondary metabolites of EPs7630[R] are bioavailable and exhibit antioxidant activities in vivo.
Lamaison, "Sedative effect of walnut leaf extract and juglone, an isolated constituent," Pharmaceutical Biology, vol.
Smith, "Effects of the chitin synthetase inhibitor plumbagin and its 2-demethyl derivative juglone on insect ecdysone 20-monooxygenase activity," Experientia, vol.
Terzi, "Allelopathic effects of Juglone and decomposed walnut leaf juice on muskmelon and cucumber seed germination and seedling growth," African Journal of Biotechnology, vol.
Because phosphorylation at proline-directed sites causes cis-isomerization of the protein backbone, we tested this effect on DAT T53 by inhibiting Pin1, a peptidyl prolyl isomerase which catalyzes the isomerization of pThr/pSer backbones using a small molecule inhibitor, juglone. Juglone treatment resulted in the accumulation of pThr53 suggesting a role for Pin1 in regulating rDAT T53 phosphorylation and thereby its function.
The black walnut (Juglans nigra) produces the allelochemical juglone, which affects some species greatly while others not at all.