Karyopyknosis


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Related to Karyopyknosis: pycnotic, caseous necrosis
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Karyopyknosis

 

shrinkage of a cell nucleus; one of the stages of necrobiosis preceding karyorrhexis and karyolysis.

The karyopyknotic nucleus shrinks because of a loss of water.It stains more intensively with basic dyes than does the nucleus of a normally functioning cell, since the nucleic acid, which isresponsible for such staining, splits off from the nucleoproteins in the nucleus.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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(b) Karyopyknosis and cytoplasmic vacuolation, H&E stain.
Ameliorative Effect of Propolis Against Hepatorenal Alterations Induced by Methotrexate: Morphohistopathological Study/Efecto Protector del Propoleo en las Alteraciones Hepatorrenales Inducidas por el Metotrexato: Estudio Morfohistopatologico
Normal structure of renal glomeruli and tubules in the sham group is shown in A and B; protein casts (yellow arrows) and erythrocytes (green arrows) were found in renal tubule lumens of rats in the shock and shock+drainage + NaHS groups, as shown in C and I; tubular epithelial cells with necrosis (yellow arrows) and karyopyknosis (green arrows) were observed in the shock and shock+drainage + NaHS groups, as shown in D and J; nearly normal architecture of glomeruli and tubules in the shock+drainage and shock+drainage + PPG groups is shown in E, F, G, and H, plus mild edema of tubular epithelial cells (yellow arrows) in H.
Hydrogen sulfide in posthemorrhagic shock mesenteric lymph drainage alleviates kidney injury in rats
Morphological studies further revealed that vitexin ameliorated neuronal damage from I/R, including cell swelling, karyopyknosis and disintegration of nucleoli.
Vitexin protects brain against ischemia/reperfusion injury via modulating mitogen-activated protein kinase and apoptosis signaling in mice
In the present study, exposure of acute concentrations of copper sulphate (E-1), lead nitrate (E-2) and their combination (E-3) for 96 h caused karyopyknosis which is marked by irreversible condensation of chromatin in the karyopycknosis in E-3 group was followed by karyorrhexis marked by fragmentation of the nucleus in necrotic cells (Figs.
Effect of Copper Sulphate and Lead Nitrate, Administered Alone or in Combination, on the Histology of Liver and Kidney of Labeo rohita
There were karyopyknosis, chromatin agglutination and apoptosis bodies under transmission electron microscope (TEM) and DNA ladder by ultra-violet spectroscopy (UV) when NCI-H460 cells were exposed to Ardipusilloside I at different concentrations.
Ardipusilloside I purified from Ardisia pusilla competitively binds VEGFR and induces apoptosis in NCI-H460 cells
Different forms of cell nuclear alterations including karyorrhexis, karyopyknosis, and karyolysis were observed after DAPI staining (blue).
Fermented Chinese Formula Shuan-Tong-Ling Protects Brain Microvascular Endothelial Cells against Oxidative Stress Injury
The epithelium cells of endometrium had vacuoles and karyopyknosis, and intercellular gaps became bigger.
The Effect of Visfatin on Inflammatory Reaction in Uterus of LPS-Induced Rats/Efecto de Visfatina en la Reaccion Inflamatoria en el Utero de Ratas Inducidas por LPS
These abnormalities included marked binucleation, anisokaryosis, karyolysis, karyorrhexis and karyopyknosis. Some pyknotic hepatocytes of rats exhibited clumping and condensation chromatin condensation in the periphery of the nuclei together with irregularity nuclear membranes.
Hepatic Histological and Histochemical Alterations Induced by Rosuvastatin Therapeutic Doses

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