A
keloid is a tough heaped-up scar that rises above the rest of the skin.
Several treatment and prophylactic modalities including surgical excision, radiation, pressure therapy, cryotherapy, topical silicone gel, intralesional corticosteroid injections, interferons, fluorouracil, laser treatment, and many other medications have been used in the management of HS and
keloids.5-13 The aim of our study was to determine the prophylactic efficacy of topical corticosteroid ointment as a non-invasive form of therapy for post-operative HS and
keloids following Cesarean section.
However, during treatment, the
keloid lesion in the sternal notch increased in size.
A clinical trial conducted with sixty patients of
keloid attended in the Department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka for duration of January 2013 to August 2013.
Three refused participation and 04 were ineligible due to exclusion criteria (02 had uncontrolled DM and 02 had infected
keloid).
One way of looking at a tattoo is that it's ink under the skin and that alone makes it a risk in getting blood-borne diseases like HIV and hepatitis, skin infections, and of course,
keloids. Red dye for tattooing has especially been identified to cause allergic reaction resulting in an itchy rash.
This surgery was complicated by fibromatosis and
keloid scar formation, ultimately leading to amputation of the small finger.
Key words: Cicatrix, Hypertrophic;
Keloid; Models, Animal; Rabbit; Transforming Growth Factor Beta 1.
Study was conducted on 156 patients with
keloid of age about 5 years and above.
In addition to that, the difficulty in clinical distinction between
keloids and hypertrophic scars and the lack of histopathological confirmation decrease the validity of these studies.[sup][34] The absence in
keloid histological confirmation might be explained by the near-zero rate of malignancies or dysplasias.[sup][35] Therefore, due to the limitations, there are no preferred treatments of
keloids in specific sites.
The purpose of this study was to make an ideal rabbit ear
keloid model.
The pathophysiology of
keloid is still not fully elucidated yet, although changes in the expression of cytokines [4, 5], increase in fibroblast proliferation [6], and exacerbated collagen synthesis [7] have been described in the literature.