kernicterus


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Related to kernicterus: hyperbilirubinemia

kernicterus

[kər′nik·tə·rəs]
(pathology)
Deposition of bilirubin in the gray matter of the brain and spinal cord, especially the basal ganglia, accompanied by nerve cell degeneration.
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With the aggressive use of phototherapy, frank kernicterus became a rare event in affluent nations.
Bhutani VK, Johnson LH, Urgent clinical need for accurate and precise bilirubin measurements in the United States to prevent kernicterus.
When Aidan was born, he met multiple criteria that made him a high kernicterus risk.
Because Transcutaneous Bilirubin (TCB) is a measurement of tissue bilirubin, it might be a better predictor of kernicterus.
For preventing the kernicterus and other complications of hyperbilirubinaemia, jaundice should be managed by phototherapy or exchange transfusion (ECT).
Kernicterus would be largely preventable if health care personnel followed these recommendations, the guideline states (Pediatrics 114[1]:297-316, 2004).
The root causes of kernicterus are early discharge without follow-up of the infant, failure to recognize a dangerous serum bilirubin level, and failure to respond to this warning sign," said Dr.
Although kernicterus, or bilirubin encephalopathy, is preventable, it is still occurring.
Because sulfonamide therapy is known to increase the possibility of kernicterus, it is not used on premature infants during the first 2 months of life (Lockhart, Rushworth, & Azmy, 1983).
The Sheridan family experienced another healthcare system failure when their son Cal's neonatal jaundice went untreated, leading to a kind of severe brain damage called kernicterus.
High bilirubin levels may be toxic to the developing central nervous system and may cause neurological impairment like kernicterus or even fatal sometimes.
Acquired causes of CP, for instance kernicterus, meningoencephalitis and neonatal seizures, greatly contributed to a significant portion of CP in this community.