ketoprofen


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ketoprofen

(kē'təprō`fĭn), nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and fever-reducing effects, used to relieve the symptoms of headaches, arthritis, and painful menstruation. Along with ibuprofenibuprofen
, nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, fever, and inflammation. Along with naproxen and ketoprofen, ibuprofen belongs to the propionic acid class of NSAIDs. It was first made available in 1967.
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 and naproxennaproxen
and naproxen sodium,
potent nonsteroidal anti-inflammatory drugs (NSAID) used to alleviate the minor pain of arthritis, menstruation, headaches, and the like, and to reduce fever.
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, it belongs to the propionic acid class of NSAIDs; it apparently acts by inhibiting the body's production of prostaglandinsprostaglandin
, any of a group of about a dozen compounds synthesized from fatty acids in mammals as well as in lower animals. Prostaglandins are highly potent substances that are not stored but are produced as needed by cell membranes in virtually every body tissue.
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. Available as a prescription drug for more than 20 years in many countries, it was approved as an over-the-counter painkiller in the United States in 1995 and first marketed as Orudis KT. It is considered more powerful than many other NSAIDs. Side effects may include gastrointestinal disturbances and fluid retention.
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References in periodicals archive ?
Key words: Ketoprofen immunomodulatory humoral immunity immune organs.
Ketoprofen belongs to class of cyclo-oxygenase inhibitor and a non-steroidal anti-inflammatory drug (NSAID).
All the NSAIDs (diclofenac, dipyrone, etodolac, and ketoprofen) produced significant analgesic effects in the hot plate test (p<0.01 and p<0.001).
Europe dominates the global market for ketoprofen due to large number of aging population and increasing junk food habits and sedentary lifestyle.
Comparison of the efficacy and safety of intravenously administered dexketoprofen trometamol and ketoprofen in the management of pain after orthopaedic surgery: a multicentre, double-blind, randomised, parallel-group clinical trial.
Dr Campbell Murn at the Hawk Conservancy Trust said: 'With action being taken to restrict aceclofenac and ketoprofen in Pakistan, we hope this will prove to be an important influence on similar efforts in other countries in South Asia, leading to the change that is needed to protect vulture populations in the region'.
Rats were treated orally with nimesulide, ketoprofen, etoricoxib, or water, and 30 minutes or 2 hours after administration, TG were dissected and isolated as described in Methods.
Dexketoprofentrometamol (DKP), is a tromethamine salt of the water-soluble S-enantiomer of ketoprofen. It reaches its peak plasma concentration (Cmax) approximately 30 minutes after oral intake.
These results provides the basic information of immunosuppression by ketoprofen on cell mediated immunity and supports the potential application of ketoprofen in patients with allo-grafts or autoimmune diseases.
Ketoprofen lysine salt was kindly donated by Dompe SpA (LAquila, Italy); L-leucine was supplied by Sigma Aldrich (Milan, Italy).