Kinetoplast

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kinetoplast

[kə′ned·ə‚plast]
(cell and molecular biology)
A genetically autonomous, membrane-bound organelle associated with the basal body at the base of flagella in certain flagellates, such as the trypanosomes. Also known as parabasal body.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Kinetoplast

 

a cell organelle; the basal nodule of the cilia of infusoria.

The origin of the kinetoplast is associated with the centriole, an assumption supported by the similarity in ultrastructure of the two organelles. In addition to proteins, carbohydrates, and lipids, the kinetoplast contains DNA and RNA and is capable of the independent biosynthesis of protein and of self-reproduction. Kinetoplasts may give rise to cilia or trichocysts. The tendency to call all basal bodies kinetoplasts is incorrect.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Riley, "Isolation and characterization of DNA from kinetoplasts of Leishmania enriettii," Science, vol.
Caption: Figure 3: Electron microscopy images of kinetoplasts of nonpathogenic trypanosomatids.
The kinetoplast is a diagnostic structure of the Kinetoplastida order, which encompasses the Trypanosomatidae family.
The first evidence of the existence of kinetoplast came over a century ago after the discovery of a basophilic granule located near the base of trypanosome's flagellum.
The architecture of the kinetoplast is crucial for replication and segregation of the kDNA circles because the molecules involved in these processes are precisely positioned in functional domains throughout the kinetoplast (Figure 2).
Transmission electron microscopy and more recently atomic force microscopy (AFM) are powerful tools for revealing kinetoplast structure, the topological organization of kDNA, and the replication and segregation of kDNA of trypanosomatids.
Observations of thin sections of resin-embedded samples have enabled the investigation of the cell components of trypanosomatids, including kinetoplast. Using TEM, Meyer and coworkers [4] were pioneers in demonstrating that the kinetoplast (initially called the kinetonucleus) was separated from the basal body, from which the flagellum emerges.
The observation of transversal sections of kinetoplast in various trypanosomatids revealed that this structure is surrounded by the double membrane of mitochondria, from which cristae can occasionally be seen projecting into the lumen.
The kinetoplast varies in size and kDNA arrangement among species.
Molecular evidence of Leishmania species was pursued using kinetoplast minicircle DNA-specific primers.
Characteristic features of the amastigote, the intracytoplasmic kinetoplast and a rod-shaped mitochondrial structure composed of DNA, are helpful diagnostic criteria in cytology sections of patients with leishmaniasis.