However, the nonpathological lacrimal gland
dimensions in the Turkish population have not yet been reported.
Effects of extract of Buddleja officinalis on partial inflammation of lacrimal gland
in castrated rabbits with dry eye.
The orbit is an anatomically complex structure in bony socket of skull having globe, includes eye lids, eye ball, extra ocular muscles, cranial nerves, blood vessels, fat, lacrimal glands
, ducts, ciliary ganglions, supported by ligaments and different supportive muscles of the face.1,2 Inflammation or neoplastic lesions of orbit, all affect quality of life greatly.3
Old New Mikulicz's IgG4-related disease dacryoadenitis and sialadenitis Sclerosing Kuttner's tumor, sialadenitis IgG4-related submandibular gland disease Inflammatory IgG4-related orbital orbital inflammation or pseudotumor orbital inflammatory pseudotumor Chronic Lacrimal gland
sclerosing enlargement, dacryoadenitis IgG4-related dacryoadenitis Idiopathic' IgG4-related retroperitoneal retroperitoneal fibrosis, fibrosis (Ormond's IgG4-related mesenteritis disease) andrelated disorders Chronic sclerosing IgG4-related aortitis or aortitis and periaortitis periaortitis Riedel's IgG4-related thyroid thyroiditis disease IgG4-related IgG4-related lung disease interstitial pneumonitis and pulmonary inflammatory pseudotumors IgG4-RD: immunoglobulin G4-relateddisease.
Dry eye disease (DED) is a multifactorial condition involving the ocular surface, lacrimal glands
, and meibomian glands leading to abnormal tear film quantity and/or quality.
The bilateral findings were more suspicious for an inflammatory process; therefore, 1 g IV methylprednisone for a 3-day course was then initiated with marked improvement of his eyes in appearance, pain, and drainage, further suggesting an inflammatory process affecting the lacrimal glands
and surrounding tissue (as documented by CT orbits).
The main organs involved are the lymph nodes, salivary glands, lacrimal glands
, and pancreas [4-10], which is very similar to our reported cases except the second case which had IgG4-related pachymeningitis which is an extremely rare finding in our literature review.
Interestingly, NIS was demonstrated to be expressed in various normal non-thyroid tissues including salivary glands, lacrimal glands
, breasts, stomach, intestine, lungs, and kidneys [22, 23].
A, Storiform fibrosis from the lacrimal gland
biopsy shown in Figure 3, F.
Two of the most common characteristics of dry eye syndrome are the inadequacy of the water layer of tears produced by the lacrimal glands
and insufficient oil production from the meibomian glands.
On examination, he had nontender bilateral parotid gland enlargement and bilateral lacrimal gland
Therefore, it was envisioned that VAMP8 could be related to exocytosis of secretory vesicles in lacrimal gland