lactam


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Related to lactam: lactone

lactam

[′lak‚tam]
(organic chemistry)
An internal (cyclic) amide formed by heating gamma (γ) and delta (δ) amino acids; thus γ-aminobutyric acid readily forms γ-butyrolactam (pyrrolidone); many lactams have physiological activity.
References in periodicals archive ?
coli had highest resistance to penicillin and first generation cephalosporin followed by to second and third generation cephalosporins and monocyclic lactams.
Nitin specialises in manufacturing liquid ampoules, liquid vials, sterile dry powder (beta lactam and non beta lactam), multidose eye/ear drops and lyophilised vials covering more than 200 formulations across various therapeutic areas including antibiotics.
The transaction also cements our leading position in beta lactam production and provides Recipharm not only with additional scale but also opportunities to realize commercial and operational synergies as we combine it with our existing Italian business.
Results of the frequency of use of different tests for screening for p lactam antibiotics in milk were shown in Figure 1.
Cefoxitin resistant Staphylococcus aureus are resistant to all beta lactam antibiotics irrespective of their zone sizes in vitro.
Resistance to [beta]- lactam antibiotics: Resistance to penicillins and other [beta]- lactams in Gramnegative bacilli (prototype Escherichia coli) can occur by four general mechanisms.
Steroidal-4-en-3-ones such as 4-cholesten-3-one were treated with ozone to obtain a keto acid, 3,5-seco-4-norcholestan-5-on-3-oic acid (I), subsequently treated with amines to obtain enamine lactams which were discovered to react with Grignard reagents at elevated temperatures to yield novel unsaturated 3-alkyl derivativatives.
ChiroTech was recognized for its work on a bicyclic lactam molecule, which is a precursor to pharmaceutical compounds such as anti-viral, carbocylic nucleotides.
Named Hanhwa Lactam, the joint venture will have a total production capacity of 140,000 metric tons that will be executed in stages beginning with an initial annual output of 70,000 metric tons.
However, biological production of these highly valued chemicals has been limited due to a lack of enzymes that form lactam rings.
PPG Industries has received a patent for a compound that is comprised of the reaction product of a highly branched polymer having terminal amine functional groups and a lactam, wherein the highly branched polymer is the step-growth polymerization reaction product of a polyfunctional first monomer having a first functional group and a polyfunctional second monomer having a second functional group wherein the first and second functional groups will react with each other but not themselves, wherein formation of the highly branched polymer is free of self-condensation of the polyfunctional first monomer, and free of self-condensation of the polyfunctional second monomer.
9] suggested that beta lactam antibiotic should not be used when in suspected CA-MRSA infection due to the potential risk of aggravated the infection as beta-lactam antibiotics upregulated PVL messenger RNA in several in vitro studies.