lambda bacteriophage

lambda bacteriophage

[′lam·də bak¦tir·ē·ə‚fāj]
(microbiology)
A temperate phage that infects Escherichia coli and then undergoes one of two life cycles: (1) lytic, in which it infects the host cell, replicates, and causes the cell to lyse (burst) as new phage progeny emerge; or (2) lysogenic, in which it infects the bacterial host cell, integrates its deoxyribonucleic acid into the host's genome, and goes into a dormant phase during which it replicates along with the host chromosome until it is induced to undergo lytic growth.
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In the next stage, a nano-carrier for lambda bacteriophage (virus infected by bacteria) with the ability to convey in animal cells was designed and produced," he added.
The nanoparticles used in this research (lambda bacteriophage) are much more harmless and biocompatible than the materials used in previous researches due to their natural characteristics.
In the case of the lambda bacteriophage, DNA sequences up to 7 kilobases can be packaged and propagated.
Although Stocher and Berg (8) demonstrate the feasibility of using lambda bacteriophage as an exogenously added assay control, a strong concern remains to be addressed before this technology will be widely accepted.
The P1c1 repressor is functionally analogous to the c1 repressor of lambda bacteriophage. c1 binds to at least 14 unlinked operator sites which are 17 base pair (bp) sites with the asymmetric consensus sequence 5'ATTGCTCTAATAAATTT3' on the P1 genome (1, 2, 3, 7, 9, 10, 11, 15).