Ichthyosis

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Related to lamellar ichthyosis: congenital ichthyosiform erythroderma

ichthyosis

[‚ik·thē′ō·səs]
(medicine)
A congenital skin disease characterized by dryness and scales, especially on the extensor surfaces of the extremities.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Ichthyosis

 

fish skin disease, xeroderma, a skin disease characterized by sharply increased keratogenesis and retarded keratolysis.

Incidence of ichthyosis is a familial condition in half the cases and hereditary in 25 percent. It appears in early childhood (most often around age three), intensifies at puberty, and lasts throughout life. It is expressed in dryness of the skin and the accumulation of horny masses on the skin’s surface, in the form of scales or of massive horny plates that resemble fish scales. The excretion of oil and perspiration decreases sharply. The affection spreads over the entire skin surface, except at joint folds, axillae, and inguinal folds. On the face and scalp, ichthyosis appears in the form of furfuraceous desquamation. The condition of the skin improves in the summertime as a result of increased excretion of oil and sweat. Ichthyosis is treated with hot baths containing soda or table salt, followed by lubrication of the skin with emollient creams. Cod-liver oil and vitamins may be taken internally (in particular vitamin A). In the summer, prolonged sojourns in the south can be helpful (sea bathing).

I. N. VEDROVA

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Lamellar ichthyosis (LI) may be caused by mutations affecting different genes.1 There is abnormality of gene encoding for transglutaminase 1, an important epidermal enzyme responsible for cross-linking epidermal proteins during the formation and maturation of the stratum corneum.1,2
To the best of our knowledge, this is the first case of lamellar ichthyosis with rickets to be reported from Pakistan.
1) The term collodion baby is used for newborns in whom all the body surface is covered by thick skin sheets called "collodion membrane" of which lamellar ichthyosis is the most common underlying cause.
Oral retinoid (RO 10-9359) in children with lamellar ichthyosis, epidermal hyperkeratosis and symmetrical progressive erythrokeratodermia.
A case report of dental involvement in lamellar ichthyosis is presented and the dental management is discussed.