latent virus


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Related to latent virus: lytic virus

latent virus

[¦lāt·ənt ′vī·rəs]
(virology)
A virus that remains dormant within body cells but can be reactivated by conditions such as reduced host defenses, toxins, or irradiation, to cause disease.
References in periodicals archive ?
The activation of Spi-B-gene expression in transitional B cells that contain latent virus maybe an important step in viral reactivation.
Since HPVs can establish latent subclinical infections in the human host, many HPV infections in immunocompromised individuals likely represent re-activation of latent virus that may have been acquired early in life.
Most of us who have had chickenpox (which includes some 90 percent of American adults) are totally unaware of the presence of VZV--until many years later, when the latent virus may come to life, as it does in about 20 percent of persons who had childhood chickenpox.
Where possible, a waiting period for the latent virus to develop should be observed.
Current treatment focuses on suppression of the latent virus. Acyclovir, administered orally, [10,11] idoxuridine, administered iontophoretically, [7] and large oral doses of L-lysine [12] have been used with varied success.
VZ virus causes both varicella (the manifestation of primary infection in a susceptible person) and zoster (the result of reactivation of latent virus); patients with either disease may transmit the virus to susceptible persons[1-3].
Our study suggests that there may be means of activating latent virus in the body while the patient is on antiretroviral drugs to prevent the virus from spreading, and that this may eliminate at least some of the latent reservoir."
PVX is a latent virus because it can remain latent in the infected plant and therefore sometimes unable to identify on symptom basis (Ahmad et al., 2011).
"It proves the principle that a combination of drugs that activate latent virus together with antibodies can induce remission -- at least in a slightly artificial HIV-infected mouse model," stated by Professor Sharon Lewin, head of the infectious unit at The Alfred Hospital according to (http://theconversation.com/shock-and-kill-approach-cures-mice-of-hiv-in-world-first-30528) The Conversation .
Latent viral gene products with oncogenic potential include Epstein-Barr nuclear antigen-2 (EBNA2), a specific transcriptional transactivator of viral and cellular genes, and the latency membrane protein-1 (LMP-1), a transmembrane phosphoprotein.10 In circumstances in which the host's cellular immune system fails to control EBV-induced B-cell proliferation, previously latent virus can then induce malignant transformation.
Zoster indicating that disease results from the reactivation of latent virus rather than new exposures to VZV.11 However, certain studies have reported summer seasonality, and this pattern might be related to ultraviolet irradiation that peaks during summer months and might serve as a trigger for zoster.11