laudanosine


Also found in: Medical.

laudanosine

[lȯ′dan·ə‚sēn]
(organic chemistry)
C21H27NO4 An alkaloid that is the methyl ether of laudanine; the optically inactive form crystallizes from dilute alcohol and melts at about 115°C; the levorotatory active form crystallizes from light petroleum solution and melts at 89°C.
References in periodicals archive ?
As previously stated, atracurium undergoes Hofmann elimination; one of the metabolites associated with this elimination path is laudanosine, which has been reported to cross the blood-brain barrier and decrease the seizure threshold.
Use of neuromuscular blocking agents in acute respiratory distress syndrome
It is metabolized to laudanosine and ultimately excreted in the urine [26].
The Benefit of Neuromuscular Blockade in Patients with Postanoxic Myoclonus Otherwise Obscuring Continuous Electroencephalography (CEEG)
Only glaucine and laudanosine inhibited K+-induced uterine contractions more than oxytocin-induced uterine contractions.
Naturally occurring plant isoquinoline N-oxide alkaloids: their pharmacological and SAR activities
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