The protein sequence of TlyA was derived from the Leproma
web server (http://genolist.pasteur.fr/Leproma) and BLASTp was performed through the NCBI server (http://www.ncbi.nlm.nih.gov/BLAST/).
(13) Classical histopathological findings include epidermal atrophy as a result of dermal expansion of the underlying leproma
and a Grenz zone located immediately below the epidermis.
En las muestras de los pacientes 1 y 2 se detecto una mutacion puntual en el gen rpoB, localizada en el nucleotido 1367 (TCG [flecha diestra] TTG), que produce un cambio de serina por leucina en la posicion 456 de la secuencia aminoacidica, segun el sistema de numeracion empleado en la base de datos Leproma
(23) (cuadro 2).
Observations on ultrastructure of histoid leproma
. Int J Lepr, 1982; 50: 471-476.
On the basis of history and clinical examination a provisional diagnosis of verrucous carcinoma of buccal mucosa, leproma
of the tongue and pseudo-membranous candidal infection of the palate was made.
The DNA sequences of the PCR products of three genes studied were compared with the Gene sequence data base of 'Leproma
leprae suspension derived from a human leproma
in both the hind foot pads; duplicate sets were studied, (b) three control groups (48 mice each) included, i.e.
From the biopsies, a fragment of the leproma
was removed and ground in a mortar with pestle in 100 mM Tris-HCl, 150 mM NaCl, 10 mM EDTA; pH 7.4.
The histoid leproma
:its characteristics and significance.
PCR-restriction fragment length polymorphism analysis (PRA) of Mycobacterium leprae from human lepromas
and from a natural case of an armadillo of Corrientes, Argentina.