lepromin


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lepromin

[lə′prō·mən]
(immunology)
An emulsion of ground lepromata containing the leprosy bacillus; used for intradermal skin tests in Hansen's disease.
References in periodicals archive ?
Interaction of TaqI polymorphism at exon 9 of the vitamin D receptor gene with the negative lepromin response may favor the occurrence of leprosy.
The pathologist can only report on what he sees and the clinician should accept this limitation and correlate the biopsy report both with the signs he has found on examining the whole patient and with the lepromin results.
Histopathological findings can also help us to say whether the reaction is upgrading or downgrading in situations, where facilities for doing lepromin test are not available and also when the patient presents with reaction at the first visit.
Additional investigations that can be done to confirm diagnosis include lepromin testing, serology, PCR testing, and cutaneous biopsy.
The tuberculoid form is a stable aspect of the disease; the smear is negative; the lepromin is positive.
An additional test used in humans is the lepromin test (leprosy skin test).
tuberculosis display greater than 95% homology in amino acid sequence as evidenced by the conversion of both lepromin and tuberculin intradermal tests after injection of bacillus CalmetteGuerin (BCG).
They share common antigens as evidenced by conversion of both lepromin and tuberculin intradermal tests after administration of BCG.
Therefore, we aimed to correlate the clinical and bacteriological parameters with that of nasal biopsy and immunology as lepromin and ML-Flow results of untreated leprosy patients.
Lepromin A (0,1 ml) produced by the Schieffelin Leprosy Research Sanatorium, Karigiri, India, was inoculated in the left forearm of all the patients.
When administered during the initial stage of chemotherapy, success has been claimed in terms of lepromin conversion and accelerated rate of decline in bacteriological index (BI).
Although the majority of armadillos develop a lepromatous form of leprosy, the full spectrum of histopathological responses can be observed among armadillos and the animals can be classified according to the Ridley-Jopling scale from lepromatous (LL) to tuberculoid (TT) using lepromin skin testing.