leptospirosis


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leptospirosis

(lĕp'təspīrō`sĭs), febrile disease caused by bacteria of the genus Leptospirae. The disease may affect dogs, cattle, pigs, sheep, goats, and horses and is also transmissible to humans. It is most common where the climate is warm and humid, soils are alkaline, and there is abundant surface water. The source of infection in farm animals is usually through pastures, drinking water, or feed, when contaminated by infected urine, and is often a work-related risk for farmers, sewer and slaughterhouse workers, and vetinarians. Infection may also occur as a result of contact with infected uterine discharges and aborted fetuses, with infected pets, or with contaminated water while swimming or during persistent flooding. In urban areas human infections may result from contact with rat urine.

In cattle, pigs, sheep, and goats, the disease is characterized by fever, depression, anemia, and abortion. Horses develop an ocular infection. In dogs the disease causes a severe kidney infection. In humans, typical symptoms include a dry cough, fever and chills, head and muscle aches, and nausea and diarrhea. It is treated with chloramphenicol, erythromycin, or other antibiotics; untreated, it may be life-threatening. Control of leptospirosis depends on the elimination of carrier animals, appropriate hygienic measures, and vaccination of susceptible animals.

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Leptospirosis

An acute febrile disease of humans produced by spirochetes of many species of Leptospira. The incubation period is 6–15 days. Among the prominent features of the disease are fever, jaundice, muscle pains, headaches, hepatitis, albuminuria, and multiple small hemorrhages in the conjunctiva or skin. Meningeal involvement often occurs. The febrile illness subsides after 3–10 days. Fatal cases show hemorrhagic lesions in the kidney, liver, skin, muscles, and central nervous system.

Wild rodents are the principal reservoirs, although natural infection occurs in swine, cattle, horses, and dogs and may be transmitted to humans through these animals. Humans are infected either through contact with the urine or flesh of diseased animals, or indirectly by way of contaminated water or soil, the organisms entering the body through small breaks in the skin or mucous membrane.

McGraw-Hill Concise Encyclopedia of Bioscience. © 2002 by The McGraw-Hill Companies, Inc.

leptospirosis

[‚lep·tə·spə′rō·səs]
(medicine)
Infection with spirochetes of the genus Leptospira.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
If untreated, Leptospirosis can lead to kidney damage, meningitis (inflammation of the membrane around the brain and spinal cord), liver failure, respiratory distress, and even death.
Based on the data of the Department of Health Region 11 (Davao Region), a total of 44 suspected cases of leptospirosis with four deaths were recorded from January to September 2 this year.
The plague of dengue fever and leptospirosis are upon us today.
Health Secretary Francis Duque on Tuesday visited the patients confined at NKTI due to leptospirosis. Because of the number of cases, NKTI Multipurpose Hall has been converted into a leptospirosis ward, where around 30 patients are confined.
Anna De Guzman, PHO officer, has given a directive to all their hospitals to monitor all incoming patients with leptospirosis symptoms.
The diagnosis of leptospirosis was confirmed by passive hemagglutination test (the titer was 1/160).
An IgM ELISA for leptospirosis performed 5 days after admission showed a positive result.
Leptospirosis, known in most countries as a rare disease, is endemic in the Philippines.
Shailaja Teacher called a review meeting at Kozhikode, the district from where the most number of leptospirosis cases have been reported.
The diagnosis of leptospirosis should be considered in any patient that this sudden fever, chills, headache, jaundice and conjunctival injection, myalgia most notable in the areas lumbar and calves which constitute one of the symptoms most distinctive of the disease.
The serum were collected fromboth vaccinated and unvaccinated dogs and and analysed in the university Leptospirosis laboratory.
She asked people to get leptospirosis disease preventing treatment from the nearest Medical Officer of Health (MOH) office or the Public Health Inspector (PHI) free of charge before engaging in farming activities or where water still exists.