lethal dose 50


Also found in: Dictionary, Medical, Acronyms.
Related to lethal dose 50: therapeutic index, Effective dose 50, LC50

lethal dose 50

[′lē·thəl ¦dōs ′fif·tē]
(pharmacology)
The dose of a substance which is fatal to 50% of the test animals. Abbreviated LD50. Also known as median lethal dose.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Key words: Cobra venom, Hematology, Bio-physiological effects, Lethal dose 50, Mice.
Investigation of animal responses after intravenous (IV) administration of the mushroom was undertaken and relative data on established safe IV doses, lethal dose 50 (L[D.sub.50]), therapeutic index and therapeutic ratio were discussed to authenticate its prospective beneficial effect.
The HPS-LH vaccine containing more than 104.6 units of bird lethal dose 50 (LD50) when injected to 14 days old broilers and 21 days post vaccination given challenge with infection dose (100 units of LD50 of HPS-LH) showed 100 per cent protection.