lethal gene


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Related to lethal gene: epistasis

lethal gene

[′lē·thəl ′jēn]
(genetics)
A gene mutation that causes premature death in heterozygotes if dominant, and in homozygotes if recessive. Also known as lethal mutation.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Her stories covered a lot of ground, from how insurance companies might use genetics to determine coverage, to living with the knowledge of a lethal gene and employing DNA to breed dogs.
The breed became virtually extinct after developing a lethal gene that rendered a large proportion of their eggs infertile.
In one fruit fly line, the team inserted a three-part genetic time bomb: a lethal gene that disrupts signaling in cells, a switch controlling it that flips only in females, and a control for that switch that keeps it in its off state when the fly consumes the antibiotic tetracycline.
It has long been known that Queen Victoria was a carrier of the lethal gene of haemophilia, but we are presented here with the results of the first extended scientific examination of the history of haemophilia in the royal families of Europe.