leukocidin

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leukocidin

[‚lü·kə′sīd·ən]
(biochemistry)
A toxic substance released by certain bacteria which destroys leukocytes.
References in periodicals archive ?
Community-acquired infections due to Staphylococcus argenteus lineage isolates harbouring the Panton-Valentine leucocidin, France, 2014.
Kearns, "Staphylococcus aureus isolates carrying Panton-Valentine leucocidin genes in England and Wales: frequency, characterization, and association with clinical disease," Journal of Clinical Microbiology, vol.
Staphylococcal leucocidin LukE-LukD also has proposed involvement in the disease process via a cytotoxic mechanism, and in one case, series was identified in 94% of MRSA enterocolitis isolates [16].
Community-acquired methicillin-resistant Staphylococcus aureus infections in France: emergence of single clone that produces Panton-Valentine leucocidin. Clin.
What are the biological actions of Panton-Valentin leucocidin cytotoxin?
Methicillin-resistant Staphylococcus aureus containing the Panton-Valentine leucocidin gene in Germany in 2005 and 2006.
De Beenhouwer et al., "Polyclonal emergence and importation of community-acquired methicillin-resistant Staphylococcus aureus strains harbouring Panton-Valentine leucocidin genes in Belgium," Journal of Antimicrobial Chemotherapy, vol.
Staphylococcus aureus Panton-Valentin leucocidin directly targets mitochondria and induces Bax-independent apoptosis of human neutrophils.
Wright, "Staphylococcal leucocidin (Neisser-Wechsberg type) and antileucociddin," The Lancet, vol.
Staphylococcal cassette chromosome mec (SCCmec) typing, Panton-Valentine leucocidin (PVL) screening, and pulsed field gel electrophoresis (PFGE) were performed to further characterize the strains.
El clon USA300 o USA400, contienen la resistencia a la meticilina, dada por la incorporacion de un casete cromosomico del estafilococo mec tipo IVa y el gen lukF y lukS de la panton valentin leucocidin (PVL).