Leukocytosis

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leukocytosis

[‚lü·kə‚sī′tō·səs]
(medicine)
Elevation of the leukocyte count to values above the normal limit.

Leukocytosis

 

an increase in the absolute number of leukocytes in the peripheral blood.

Physiological leukocytosis occurs after eating and physical exertion. Symptomatic pathological leukocytosis develops with suppurative and inflammatory processes and with a number of infectious diseases, whether produced by specific causative agents of infection or as a result of the bone-marrow reaction to the breakdown of tissues caused by toxic agents or circulatory disorders (for example, myocardial infarction). Transient leukocytosis may result from the release of leukocytes into the blood from bone marrow or other tissues (for example, in stress). In all cases, the leukocytosis is reactive and disappears when its cause disappears. Leukocytosis may be produced by a malignant proliferation of hematopoietic tissue, as in leukemia.

REFERENCES

Kassirskii, I. A., and G. A. Alekseev. Klinicheskaia gematologiia, 4th ed. Moscow, 1970.
References in periodicals archive ?
Present study found sever leucopenia in 2 (1.7%), mild leucopenia in 24 (20.9%) and mild leucocytosis in 1 (0.9%) of the total studied population.
Furthermore, significant leucocytosis and granulocytosis due to neutrophilia with a regenerative left shift, also proved indicators of the inflammatory responses immediately incited by the hydronephrotic kidney subsequent to the renal insult; whereas, moderate lymphocytosis in the initial stages, was attributed to increased lymphopoeisis subsequent to chronic antigenic or cytokine stimulation; additionally, a significantly severe thrombocytopenia observed on Day 11 was found to coincide well with the clinical evidence of a prolonged bleeding tendency after venipuncture (Stockham and Scott, 2008).
This audit found that the population coming through the ED with diarrhoeal symptoms was predominantly HIV-positive with a low [CD4.sup.+] count, and the signs and symptoms largely suggested acute episodes of infective diarrhoea leading to renal dysfunction and leucocytosis. Nevertheless, we found that the management was for the most part inconsistent and could put the patient at risk of both antibiotic resistance, or (as is the case for the use of ciprofloxacin) antibiotic-related C.
Renal failure as leucocytosis are frequently observed by several authors during that pathology in 25 to 50%.
Laboratory tests showed hypochromic microcytic anaemia (Hb = 8.7 g/dL, ferritin = 332.5 ng/mL, serum iron=15 mcg/dL) without leucocytosis, hypoalbuminemia (1.84g/dL), hypokalemia (2.7 mEq/L) and hyponatremia (131 mEq/L).
Patients will complain of a sudden onset of warm, tender global swelling of the hands and/or feet that is occasionally accompanied by fever and leucocytosis. (5)
Mean WBC count was 6164/cmm, with leucopenia seen in 33.3% and leucocytosis in 5.12% cases.
Sweet's syndrome (Acute febrile neutrophilic dermatosis) is a rare skin disorder characrerized by fever, neutrophilic leucocytosis, and erythematous skin nodules.
Blood examination revealed polymorphonuclear leucocytosis (16,000/cumm, neutrophils- 85%) but culture was sterile.
At both 4 and 18 h, DEP caused systemic inflammation characterized by leucocytosis, increased IL-6 concentrations and reduced systolic blood pressure (SBP).
She had leucocytosis 15.8 x109 with neutrophilia 14.14x109 and her CRP was 19 mg/L.
On investigation, there was leucocytosis. Serology for ANA and other connective tissue markers were negative.