leukaemia

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leukaemia

(esp US), leukemia
an acute or chronic disease characterized by a gross proliferation of leucocytes, which crowd into the bone marrow, spleen, lymph nodes, etc., and suppress the blood-forming apparatus
References in periodicals archive ?
Hence, MDR1 overexpression in leukaemic cells is associated with lower CR rate and higher relapsed rate in acute leukaemia, especially in old age.27
Linn, "Immune checkpoint inhibitors enhance cytotoxicity of cytokine-induced killer cells against human myeloid leukaemic blasts," Cancer Immunology, Immunotherapy, vol.
A quantitative reverse transcriptase polymerase chain reaction method for the detection of leukaemic cells with t(8;21) in peripheral blood.
Human K562 myelogenous leukaemia cells, THP-1 acute monocytic leukaemia cells, CCRF-CEM leukaemic lymphoblast cells and CCRF-CEM/C1 CPT-resistant leukaemic lymphoblast cells were obtained from the American Type Culture Collection (ATCC, UK).
The most common cause is acute lymphoblastic leukaemia, where the normal bone marrow is being replaced by leukaemic blasts.
Differences in the distribution of CD34 epitopes on normal haemopoietic progenitor cells and leukaemic blastcells.
Dr Abuljadayel said: 'The entire blood system was created from these leukaemic cells.
But not all babies born with the "leukaemic gene" called TEL-AML 1 in their blood go on to develop the disease, suggesting it could be triggered by a second "event" after birth.
Pitfalls in the immunophenotyping of leukaemia and leukaemic lymphomas: survey of 9 years of quality control in The Netherlands.
Now researchers from St Jude Children's Hospital, Memphis, Tennessee, have found that by identifying cancer cells left over after treatment using a technique capable of detecting one leukaemic cell among 10,000 normal cells, the possibility of a relapse can be predicted.
The term acute historically referring to a rapid onset and promptly fatal outcome, now indicates the relatively undifferentiated nature of the leukaemic cells.
Results: A higher proportion of human parvovirus B19-positive cases was found in leukaemic patients (n=19; 47.5%) compared to 12 (20%) in the control group (p(less than)0.05).