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Related to Leukoderma: vitiligo


Defective skin pigmentation, especially the congenital absence of pigment in patches or bands.



a disorder of the pigmentation of the skin manifested by a decrease in or complete loss of pigment.

Leukoderma can develop from previous skin lesions (seborrheic eczema, psoriasis, parapsoriasis, lichen ruber, pityriasis versicolor) or from certain medications (Chrysorabin, Psoriasin, pyrogallol), or as a symptom of a systemic disease (for example, secondary syphilis). It is characterized by the appearance on the skin of round depigmented spots of various size surrounded by hyperpigmentation. Syphilitic leukoderma develops three to six months after infection with syphilis and concentrates mainly on the posterolateral surface of the neck (less commonly, on the back, abdomen, and lateral surface of the chest). Leukoderma patients have no subjective sensations associated with the disease. Treatment is directed at the primary condition.


Mnogotomnoe rukovodstvo po dermato-venerologii, vols. 1–3. Moscow, 1959–64.
Mashkilleison, L. N. Chastnaia dermatologiia. Moscow, 1965.


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References in periodicals archive ?
In Susruta Samhita (SS) (500 BC), one will find the term kilasa for leukoderma, and also a clear differential diagnosis involving leprosy kustha.
Nine clinical cases of leukoderma in 4 to 7 year old Marathwadi buffaloes from Latur district of Marathwada, Maharashtra, India and its surrounding area were thoroughly investigated from onset of treatment to complete recovery.
Key words: Vitiligo, vitiligo-like depigmentation, leukoderma
So far there has been no knowledge of any kind of permanent and certain treatment for curing Leukoderma.
Friedman PM, Geronemus RG: Use of the 308-nm excimer laser for postresurfacing leukoderma.
Of note, none, of the patients had evidence of idiopathic vitiligo or other causes of leukoderma.
The leukoderma of tinea versicolor is due to the inhibitory effect of the organism on pigmentation and tanning.
Use of the Daytrana patch (methylphenidate transdermal system) for attention-deficit/hyperactivity disorder (ADHD) may result in chemical leukoderma, Food and Drug Administration officials warned in a statement.
Rarely biopsy may be needed to differentiate from other hypopigmentation disorders such as Lupus erythematosus , Pityriasis alba, Tuberculoid leprosy, Post inflammatory hypopigmentation, Tinea versicolor, Piebaldism, Idiopathic guttate hypomelanosis, Progressive macular hypomelanosis, Chemical leukoderma, Post-inflammatory hypomelanosis and Primary adrenal insufficiency.
While contact dermatitis discoloration of nails and postinflammatory hyperpigmentation are categorized as acute and higher concentrations of hydroquinone lead to irreversible hypopigmentation leading to leukoderma.
glabra, such as Zhongjiefeng extract, Zhongjiefeng tablets, and Xuekang capsules, are mainly used for the treatment of pharyngolarygitis, acute influenza, pneumonia, shigellosis, cellulitis, appendicitis, thrombocytopenia, leukoderma vitiligo, and abscess (National Commission of Chinese Pharmacopoeia 2010).
Topical immunotherapy can lead to certain side effects such as persistent dermatitis, painfull cervical lymphadenopathy, generalized eczema, blistering, contact leukoderma, and urticarial reaction.