limb bud


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limb bud

[′lim ‚bəd]
(embryology)
A mound-shaped lateral proliferation of the embryonic trunk; the anlage of a limb.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The limb buds appear as outpocketings from the ventrolateral body wall at the end of fourth week of development.
Experimental work12 clearly elucidates the requirement of retinoic acid for the initiation of outgrowth in the chick limb bud. Studies have shown that phenytoin causes an altered expression of various genes involved in key morphogenetic events13.
Wada, "The apical ectodermal ridge (AER) can be re-induced by wounding, wnt-2b, and fgf-10 in the chicken limb bud," Developmental Biology, vol.
On the cellular level, the differentiation of limb bud into separate digits occurs via a complicated cascade of molecular signaling and pathways.
For example, in the developing limb bud, tissue regression has been largely associated to the molecular control of self-induced cell death (apoptosis).
After the germdisc elongates to form the germband, it begins to fold from the posterior ventral side, after which limb bud elongation occurs.
(3-5) The precise aetiology is unknown; however, there are many hypotheses suggesting that it is due to fibrofatty tumours impinging on nerves supplying the enlarged digit, or due to alteration of somatic cells during limb bud development.
The effect of cell population density on the developmental fate of reaggregating mouse limb bud mesenchyme.
According to the Hamburger-Hamilton chicken embryonic developmental stage descriptions, limb bud should appear between developmental stages HH16 to HH18.
pugilator normal anecdysis to proecdysis and in proecdysis in limb bud regeneration is marked by large transient peaks in ecdysones.
Amphibians are able to regenerate lost limbs, but retinoids can scramble the genetic information at the site of a new limb bud, resulting in multiple legs.
"If an unfortunate tadpole happens to land, they hone in on it, punch a hole in its skin, and squeeze in." The process takes 30 seconds, but a fluke burrowed in a tadpole's limb bud can cause an extra leg to sprout.