lincomycin


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lincomycin

(lĭng'kōmī`sĭn), antibioticantibiotic,
any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms. Types of Antibiotics
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 isolated from bacteria of the genus Streptomyces. Similar in activity to erythromycinerythromycin
, any of several related antibiotic drugs produced by bacteria of the genus Streptomyces (see antibiotic). Erythromycin is most effective against gram-positive bacteria such as pneumococci, streptococci, and some staphylococci (see Gram's stain).
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, it is effective against most gram-positive organisms including staphylococci, some streptococci, and anaerobic bacteria of the genus Clostridium (see Gram's stainGram's stain,
laboratory staining technique that distinguishes between two groups of bacteria by the identification of differences in the structure of their cell walls. The Gram stain, named after its developer, Danish bacteriologist Christian Gram, has become an important tool
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). Diarrhea and nausea are common side effects of the drug.
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lincomycin

[‚liŋ·kə′mīs·ən]
(microbiology)
C18H34O6N2S·HCl A monobasic crystalline antibiotic, produced by Streptomyces lincolnensis, that is active as lincomycin hydrochloride mainly toward gram-positive microorganisms.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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We must take into account the constitutive MLSB phenotype in which an enzyme methylates the 23s rRNA, altering the receptor affinities of not only macrolides, but also lincomycins and streptogramins (21).
Concentrations in surface waters and groundwater were 0.36 [micro]g/l of lincomycin and 1.5 [micro]g/l of tylosin [15], whereas concentrations in treated water were generally below 5 x [10.sup.-2] [micro]g/l (or 50ng/l) [16].
Additionally, all isolates but 1 were susceptible to kanamycin (MIC [less than or equal to]128 mg/L), and 12 isolates showed susceptibility to linezolid (MICs <2 mg/L), streptomycin (MICs [greater than or equal to]2,048 mg/L), and lincomycin ([greater than or equal to]8 mg/L).
According to their study, Gentamicin was (96.15%), enrofloxacin (92.31%), Trimethoprim-sulpha (88.46%), Amoxicillin (84.62%), Tetracycline (80.72%), Tylosin (80.77%), Lincomycin (76.92%), Ampicillin (46.15%) and Pencillin G (42.31%) effective against SCM in goats.
Staphylococcus aureus showed the least resistance, being susceptible to ciprofloxacin, norfloxacin, gentamicin, lincomycin, streptomycin, ofloxacin, and pefloxacin.
The feces of mice were collected in the control stage (day 0, with no treatment), modeling stage (day 5, with the inoculation of lincomycin hydrochloride), treatment stage (day 10, with the drug treatment), and recovery stage (day 17, with no management).
Table 1 : Antibiotic disc used for AST Antibiotics Concentration/disc Ampicillin 10 [micro]g Cloxacillin 30 [micro]g Amoxicillin/ Clavulinic acid 30 [micro]g Gentamicin 30 [micro]g Chloramphenicol 30 [micro]g Enrofloxacillin 10 [micro]g Ciprofloxacillin 10 [micro]g Erythromycin 15 [micro]g Ceftriaxone 30 [micro]g Amikacin 30 [micro]g Azithromycin 30 [micro]g Polymixin-B 10 [micro]g Lincomycin 15 [micro]g Cephalexin 30 [micro]g Table 2: Microbial prevelance in otitis Dog breeds No of Bacteria Isolated Number and samples frequency(%) Labrador 25 Staphylococci sp.
Table 1: Antibiotics used for culture sensitivity Antibiotic agent for gram-positive bacteria Disc content ([micro]g) Ampicillin + sulbactam 20 Cotrimoxazole 25 Tetracycline 30 Cefotaxime 30 Ciprofloxacin 5 Levofloxacin 5 Linezolid 30 Cloxacillin 1 Roxithromycin 15 Cephalexin 30 Lincomycin 2 Gentamicin 10 Ampicillin + sulbactam 20 Cotrimoxazole 25 Cefotaxime 30 Ciprofloxacin 5 Tetracycline 30 Gentamicin 10 Piperacillin 100 Chloramphenicol 30 Ceftizoxime 30 Ofloxacin 5 Amikacin 30 Gatifloxacin 10 Table 2: Frequency of organisms isolated by culture Organism No.
Other topical modalities introduced recently in treatment of melasma include zinc sulphate lincomycin and linoleic acid either alone or in combination with hydroquinone and betamethasone valerate.
Photodegradation of lincomycin and diazepam in sewage treatment plant effluent by photo-Fenton process.