lipophilic


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lipophilic

[¦lip·ə¦fil·ik]
(chemistry)
Having a strong affinity for fats.
Promoting the solubilization of lipids.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
"Our study examined the effects that both lipophilic and hydrophilic statins had on a key biological system that is crucial for maintaining the normal function of the placenta, which acts as the nutrient-waste exchange barrier between mother and fetus," the expert added.
In the body, lipophilic chemicals are stored and equilibrated in tissue compartments with high fat content (e.g., breast milk and adipose tissue).
Because the lowest relative lipid concentrations in milk occur during the first week after birth, when the milk is colostrum, transfer of highly lipophilic chemicals would be less likely to occur during early lactation.
'Lipophilic Statins and Risk of Hepatocellular Carcinoma and Mortality in Patients with Chronic Viral Hepatitis: Results from A Nationwide Swedish Population'.
Simon, M.D., M.P.H., from Massachusetts General Hospital in Boston, and colleagues examined the correlation between lipophilic or hydrophilic statin use and HCC incidence and mortality in a prospective propensity score-matched cohort of patients 18 years or older with confirmed chronic hepatitis B virus or hepatitis C virus infection.
Researchers found lipophilic statins were associated with reduced incidence and mortality of hepatocellular carcinoma (HCC) - a common type of liver cancer.
The four new patents granted are as follows: Methods for formulating orally ingestible compositions comprising lipophilic active agents as well as Food and beverage compositions infused with lipophilic active agents and methods of use thereof.
According to the company, Melflufen is a lipophilic peptide-conjugated alkylator that rapidly delivers a highly cytotoxic payload into myeloma cells through peptidase activity.
Effectively including lipophilic bioactives in foods and beverages is a major challenge.
SPCI is focused on developing, manufacturing and commercializing pharmaceutical products, including those based on its proprietary ALT platform which is designed to enhance the bioavailability, reduce the food effect, and improve the efficacy of lipids and lipophilic active pharmaceutical ingredients.
Harmful Algae Blooms (HAB), frequently affects these regions with the presence of microalgae producers of Paralytic Shellfish Toxins (PST), lipophilic toxins, and Domoic Acid (DA) during the summer period, with the consequent risk to public health, productive activities, and geographic dispersion towards sectors free of these toxic microalgae.