Today s approval of Yondelis provides a treatment option for advanced or metastatic liposarcoma
Neoadjuvant and adjuvant radiation therapy has led to decreased recurrence rates in liposarcomas
in general; however, data for its use in orbital liposarcoma
are scarce (8, 9).
Here, for the first time in literature, we describe the unexpected onset of heavy toxicity, including rhabdomyolysis, after the fourth course of trabectedin in a patient with retroperitoneal liposarcoma
who at the same time was taking an alternative herbal medicine suspected of triggering this adverse event.
Atypical lipomatous tumour/Well differentiated liposarcoma
Note the abundant myxoid background stroma that may also be seen in liposarcoma
and embryonal rhabdomyosarcoma.
Companies have long ignored liposarcoma
, seeing no market for drugs to treat a cancer that strikes so few.
The lesion was resected under the presumed diagnosis of low-grade liposarcoma
or atypical lipoma.
began as a partnership with her late husband, who died from liposarcoma
in 2001 while they were growing their business and their two children were young.
However, terminal differentiation of human liposarcoma
cells could be induced by ligands for PPAR[gamma] and RXR (Tontonoz et al.
Dad-of-two Paul Allen had been suffering from liposarcoma
which started in his spine and spread through his body.
The C-RADS classification of extracolonic findings ranges from 0 (technical failure) to 4 (a potentially significant finding such as a renal mass or liposarcoma
The commonest soft-tissue malignancies are synovial sarcoma, liposarcoma
and malignant fibrous histiocytoma.